Details:

Alternative Title:
J Dev Behav Pediatr
Personal Author:
Talge, Nicole M. ; Holzman, Claudia ; Van Egeren, Laurie A. ; Symonds, Laura L. ; Scheid, Jeanette M. ; ... More +
Talge, Nicole M. ; Holzman, Claudia ; Van Egeren, Laurie A. ; Symonds, Laura L. ; Scheid, Jeanette M. ; Senagore, Patricia K. ; Sikorskii, Alla Less -
Description:
Objective

Late-preterm birth (LPB: 34–36 weeks) has been associated with an increased risk of attention problems in childhood relative to full-term birth (FTB: ≥ 37 weeks), but little is known about factors contributing to this risk. We investigated the contributions of clinical circumstances surrounding delivery using follow-up data from the Pregnancy Outcomes and Community Health (POUCH) Study.

Methods

Women who delivered late-preterm or full-term and completed the sex- and age-referenced Conners’ Parent Rating Scales-Short Form: Revised (CPRS-R:S) were included in the present analysis (N=762: children’s ages: 3–9 years). The CPRS-R:S measures dimensions of behavior linked to attention problems, including: oppositionality, inattention, hyperactivity, and a global attention problem index. Using general linear models, we evaluated whether LPB subtype (medically indicated (MI) or spontaneous) was associated with these dimensions relative to FTB.

Results

After adjustment for parity, socio-demographics, child age, and maternal symptoms of depression and serious mental illness during pregnancy and at the child survey, only MI LPB was associated with higher hyperactivity and global index scores (mean difference from FTB=3.8 [95%CI 0.5,7.0] and 3.1 [95%CI 0.0, 6.2]). These findings were largely driven by children between 6 and 9 years. Removal of women with hypertensive disorders during pregnancy (N=85) or placental findings related to hypertensive conditions (obstruction, decreased maternal spiral artery conversion; N=134) reduced the differences below significance thresholds.

Conclusion

Among LPBs, only MI LPB was associated with higher levels of parent-reported childhood attention problems, suggesting that complications motivating medical intervention during the late-preterm period mark increased risk for such problems. Hypertensive disorders appear to play a role in these associations.


Subjects:
[+]
Adult Age Factors Article Attention Attention Deficit And Disruptive Behavior Disorders Attention Deficit Disorder With Hyperactivity Child Child, Preschool Delivery, Obstetric Female Humans Male Mothers Placenta Diseases Pregnancy Pregnancy Complications, Cardiovascular Pregnancy Outcome Premature Birth Social Adjustment
Source:
J Dev Behav Pediatr. 33(5):405-415.
Pubmed ID:
22487695
Pubmed Central ID:
PMC3369000
Document Type:
Journal Article
Funding:
HD34543/HD/NICHD NIH HHS/United States ; R01 HD034543/HD/NICHD NIH HHS/United States ; R01 MH064769/MH/NIMH NIH HHS/United States ; U01 DP000143-01/DP/NCCDPHP CDC HHS/United States ; UL1 TR000448/TR/NCATS NIH HHS/United States
HD34543/HD/NICHD NIH HHS/United States ; R01 HD034543/HD/NICHD NIH HHS/United States ; R01 MH064769/MH/NIMH NIH HHS/United States ; U01 DP000143-01/DP/NCCDPHP CDC HHS/United States ; UL1 TR000448/TR/NCATS NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:8ece1a2381b1674a597678fd7db51028d482a55615c9eb932aa0333576c0454a
Download URL:
https://stacks.cdc.gov/view/cdc/33380/cdc_33380_DS1.pdf
File Type:

Supporting Files

• 	nihms371999.nxml	txt
  	nihms371999f1.gif	gif
  	nihms371999f1.jpg	jpeg

More +