Disseminated Enteroviral Infection Associated with Obinutuzumab

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Dendle, Claire ; Gilbertson, Michael ; Korman, Tony M. ; Golder, Vera ; Morand, Eric ; Opat, Stephen
• Description:
  Two cases of disseminated enteroviral infection occurred in patients who received the CD20 monoclonal antibody obinutuzumab. Clinical features included hepatitis, edema, and a dermatomyositis-like syndrome. These manifestations may be unfamiliar to clinicians and are possibly responsive to intravenous immunoglobulin. Clinicians should remain vigilant for enteroviral infections in patients receiving obinutuzumab.
• Subjects:
  Adult Antibodies, Monoclonal Antibodies, Monoclonal, Humanized Antineoplastic Agents CD 20 Monoclonal Antibody Dermatomyositis Diagnosis, Differential Dispatch Disseminated Enteroviral Infection Associated With Obinutuzumab Enterovirus Enterovirus Infections Female Humans Lymphoma Meningoencephalitis Middle Aged Obinutuzumab Rituximab Viruses

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• Source:
  Emerg Infect Dis. 21(9):1661-1663
• Pubmed ID:
  26291712
• Pubmed Central ID:
  PMC4550142
• Document Type:
  Journal Article
• Volume:
  21
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:63138129cf280d978bedf0cd6fd87ba20df70a58947810b0c2d044bc86360057
• Download URL:
  https://stacks.cdc.gov/view/cdc/33146/cdc_33146_DS1.pdf
• File Type:
  [PDF - 965.09 KB ]