Causes of Death in HIV-infected Persons Who Have Tuberculosis, Thailand

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Cain, Kevin P. ; Anekthananon, Thanomsak ; Burapat, Channawong ; Akksilp, Somsak ; Mankhatitham, Wiroj ; Srinak, Chawin ; Nateniyom, Sriprapa ; Sattayawuthipong, Wanchai ; Tasaneeyapan, Theerawit ; Varma, Jay K.
• Description:
  Up to 50% of persons with HIV and a diagnosis of tuberculosis (TB) in Thailand die during TB treatment. In a prospective observational study, a team of physicians ascribed the cause of death after reviewing verbal autopsies (interviews of family members about events preceding death), laboratory data, and medical records. Of 849 HIV-infected TB patients enrolled, 142 (17%) died. The cause of death was TB for 38 (27%), including 6 with multidrug-resistant TB and 20 with disseminated TB; an HIV-associated condition other than TB for 50 (35%); and a condition unrelated to TB or HIV for 22 (15%). Twenty-three patients (16%) were judged not to have had TB at all. Death from all causes except those unrelated to TB or HIV was less common in persons receiving antiretroviral therapy (ART). In addition to increasing the use of ART, death rates may be reduced through expanded use of modern TB diagnostic techniques.
• Subjects:
  Adolescent Adult AIDS-Related Opportunistic Infections Antitubercular Agents Cause Of Death HIV Infections Humans Mycobacterium Tuberculosis Research Tuberculosis, Multidrug-Resistant Tuberculosis, Pulmonary Young Adult

  More +
• Source:
  Emerg Infect Dis. 15(2):258-264.
• Document Type:
  Journal Article
• Place as Subject:
  Thailand
• Location:
  Asia
• Volume:
  15
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:f7bc3a7149482e434b99effb6e7aa74f0a6c43a4b0fca0626a37a58addbbfb72
• Download URL:
  https://stacks.cdc.gov/view/cdc/3216/cdc_3216_DS1.pdf
• File Type:
  [PDF - 161.58 KB ]