Multidrug-Resistant Tuberculosis 
Outbreak among US-bound Hmong 
Refugees, Thailand, 2005

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Oeltmann, John E. ; Varma, Jay K. ; Ortega, Luis ; Liu, Yecai ; O’Rourke, Thomas ; Cano, Maria ; Harrington, Theresa ; Toney, Sean ; Jones, Warren ; Karuchit, Samart ; Diem, Lois ; Rienthong, Dhanida ; Tappero, Jordan W. ; Ijaz, Kashef ; Maloney, Susan A.
• Description:
  In January 2005, tuberculosis (TB), including multidrug-resistant TB (MDR TB), was reported among Hmong refugees who were living in or had recently immigrated to the United States from a camp in Thailand. We investigated TB and drug resistance, enhanced TB screenings, and expanded treatment capacity in the camp. In February 2005, 272 patients with TB (24 MDR TB) remained in the camp. Among 17 MDR TB patients interviewed, 13 were found to be linked socially. Of 23 MDR TB isolates genotyped, 20 were similar according to 3 molecular typing methods. Before enhanced screening was implemented, 46 TB cases (6 MDR TB) were diagnosed in the United States among 9,455 resettled refugees. After enhanced screening had begun, only 4 TB cases (1 MDR TB), were found among 5,705 resettled refugees. An MDR TB outbreak among US-bound refugees led to importation of disease; enhanced pre-immigration TB screening and treatment decreased subsequent importation.
• Subjects:
  Antitubercular Agents Bacterial Typing Techniques Disease Outbreaks DNA, Bacterial Drug Resistance, Multiple, Bacterial Humans Mass Screening Mycobacterium Tuberculosis Refugees Research Sputum Tuberculosis, Multidrug-Resistant

  More +
• Source:
  Emerg Infect Dis. 14(11):1715-1721
• Pubmed ID:
  18976554
• Pubmed Central ID:
  PMC2630728
• Document Type:
  Journal Article
• Place as Subject:
  Thailand ; United States
• Location:
  Asia ; North America
• Volume:
  14
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:c2456cc90b309212ed210ff2dce1f15e2f7dfb1c94535a9a63bddb58d1b50c22
• Download URL:
  https://stacks.cdc.gov/view/cdc/3194/cdc_3194_DS1.pdf
• File Type:
  [PDF - 178.07 KB ]