Using Standardized Diagnostic Instruments to Classify Children with Autism in the Study to Explore Early Development

Wiggins, Lisa D.; Reynolds, Ann; Rice, Catherine E.; Moody, Eric J.; Bernal, Pilar; Blaskey, Lisa; Rosenberg, Steven A.; Lee, Li-Ching; Levy, Susan E.

doi:10.1007/s10803-014-2287-3

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Using Standardized Diagnostic Instruments to Classify Children with Autism in the Study to Explore Early Development

Published Date:

May 2015

Publisher's site:

http://dx.doi.org/10.1007/s10803-014-2287-3

Source:

J Autism Dev Disord. 2014; 45(5):1271-1280.

[PDF-560.76 KB]

Details:

Alternative Title:

J Autism Dev Disord

Personal Author:

Wiggins, Lisa D. ; Reynolds, Ann ; Rice, Catherine E. ; Moody, Eric J. ; Bernal, Pilar ; ... More ▼

Description:

The Study to Explore Early Development (SEED) is a multi-site case-control study designed to explore the relationship between autism spectrum disorder (ASD) phenotypes and etiologies. The goals of this paper are to (1) describe the SEED algorithm that uses the Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule (ADOS) to classify children with ASD, (2) examine psychometric properties of different ASD classification methods, including the SEED method that incorporates rules for resolving ADI-R and ADOS discordance, and (3) determine whether restricted interests and repetitive behaviors were noted for children who had instrument discordance resolved using ADI-R social and communication scores. Results support the utility of SEED criteria when well-defined groups of children are an important clinical or research outcome.

Subject:

[+]

Pubmed ID:

25348175

Pubmed Central ID:

PMC4486213

Document Type:

Journal Article

Funding:

LSW0/Intramural CDC HHS/United States ; U10DD000180/DD/NCBDD CDC HHS/United States ; U10DD000181/DD/NCBDD CDC HHS/United States ; U10DD000182/DD/NCBDD CDC HHS/United States ; U10DD000183/DD/NCBDD CDC HHS/United States ; ... More ▼

Collection(s):

CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

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