Using Standardized Diagnostic Instruments to Classify Children with Autism in the Study to Explore Early Development

Wiggins, Lisa D.; Reynolds, Ann; Rice, Catherine E.; Moody, Eric J.; Bernal, Pilar; Blaskey, Lisa; Rosenberg, Steven A.; Lee, Li-Ching; Levy, Susan E.

doi:10.1007/s10803-014-2287-3

i

Using Standardized Diagnostic Instruments to Classify Children with Autism in the Study to Explore Early Development

Supporting Files

May 2015
By Wiggins, Lisa D. ; Reynolds, Ann ; Rice, Catherine E. ; ...

Details

Alternative Title:

J Autism Dev Disord
Personal Author:

Wiggins, Lisa D. ; Reynolds, Ann ; Rice, Catherine E. ; Moody, Eric J. ; Bernal, Pilar ; Blaskey, Lisa ; Rosenberg, Steven A. ; Lee, Li-Ching ; Levy, Susan E.
Description:

The Study to Explore Early Development (SEED) is a multi-site case-control study designed to explore the relationship between autism spectrum disorder (ASD) phenotypes and etiologies. The goals of this paper are to (1) describe the SEED algorithm that uses the Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule (ADOS) to classify children with ASD, (2) examine psychometric properties of different ASD classification methods, including the SEED method that incorporates rules for resolving ADI-R and ADOS discordance, and (3) determine whether restricted interests and repetitive behaviors were noted for children who had instrument discordance resolved using ADI-R social and communication scores. Results support the utility of SEED criteria when well-defined groups of children are an important clinical or research outcome.
Subjects:

ADI-R ADOS Article Autism Classification Phenotypes Study Methods
Source:

J Autism Dev Disord. 2014; 45(5):1271-1280.
Pubmed ID:

25348175
Pubmed Central ID:

PMC4486213
Document Type:

Journal Article
Funding:

LSW0/Intramural CDC HHS/United States ; U10DD000180/DD/NCBDD CDC HHS/United States ; U10DD000181/DD/NCBDD CDC HHS/United States ; U10DD000182/DD/NCBDD CDC HHS/United States ; U10DD000183/DD/NCBDD CDC HHS/United States ; U10DD000184/DD/NCBDD CDC HHS/United States ; U10DD000498/DD/NCBDD CDC HHS/United States
Volume:

45
Issue:

5
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:286e22da8253be5bba2953047a185f9414d5a5b97d7c532b51871d1007c513a4
Download URL:

https://stacks.cdc.gov/view/cdc/31882/cdc_31882_DS1.pdf
File Type:

[PDF - 560.76 KB ]

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