Sex Differences on the ADOS-2

Details

• Alternative Title:
  J Autism Dev Disord
• Personal Author:
  Rea, Hannah M. ; Øien, Roald A. ; Shic, Frederick ; Webb, Sara Jane ; Ratto, Allison B.
• Description:
  The sex difference in the prevalence of autism spectrum disorder (ASD) may be magnified by sex differences on diagnostic measures. The current study compared autistic males and females on items on the gold-standard diagnostic measure, the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2). In a sample of 8-to-17-year old autistic individuals from research (n = 229) and clinical settings (n = 238), females were less likely to show atypicalities on most items related to social-communication behaviors and on total and subscale scores. When controlling for overall intensity of symptomatology, no sex differences survived statistical corrections. Diagnostic criteria and/or gold-standard assessments may be less sensitive to female presentations of ASD and/or autistic females may exhibit fewer or less intense behaviors characteristic of ASD.
• Subjects:
  Adolescent Autism Spectrum Disorder Autistic Disorder Child Communication Female Humans Male Sex Characteristics Social Behavior
• Keywords:
  ADOS Autism Diagnosis Sex Differences
• Source:
  J Autism Dev Disord. 53(7):2878-2890
• Pubmed ID:
  35451672
• Pubmed Central ID:
  PMC10074828
• Document Type:
  Journal Article
• Funding:
  P50 HD103524/HD/NICHD NIH HHSUnited States/ ; R01 MH100028/MH/NIMH NIH HHSUnited States/ ; R01 OH010028/OH/NIOSH CDC HHSUnited States/ ; U54 HD090257/HD/NICHD NIH HHSUnited States/
• Volume:
  53
• Issue:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:159b5020293b72c3ddde75dd0d6fd929f5e2dcb9a303d200280f01d2cf68a0e71c9bef4c9b5821ca6d98d877ee10bad0d7ccb219b20a25a96cc8ca03f1c7a4ed
• Download URL:
  https://stacks.cdc.gov/view/cdc/130344/cdc_130344_DS1.pdf
• File Type:
  [PDF - 545.69 KB ]