Risk Factors for Nipah Virus Encephalitis in Bangladesh1

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Montgomery, Joel M. ; Hossain, Mohamed J. ; Gurley, E. ; Carroll, D.S. ; Croisier, A. ; Bertherat, E. ; Asgari, N. ; Formenty, P. ; Keeler, N. ; Comer, J. ; Bell, M.R. ; Akram, K. ; Molla, A.R. ; Zaman, K. ; Islam, Mohamed R. ; Wagoner, K. ; Mills, J.N. ; Rollin, P.E. ; Ksiazek, T.G. ; Breiman, R.F.
• Description:
  Nipah virus (NiV) is a paramyxovirus that causes severe encephalitis in humans. During January 2004, twelve patients with NiV encephalitis (NiVE) were identified in west-central Bangladesh. A case-control study was conducted to identify factors associated with NiV infection. NiVE patients from the outbreak were enrolled in a matched case-control study. Exact odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by using a matched analysis. Climbing trees (83% of cases vs. 51% of controls, OR 8.2, 95% CI 1.25-infinity) and contact with another NiVE patient (67% of cases vs. 9% of controls, OR 21.4, 95% CI 2.78-966.1) were associated with infection. We did not identify an increased risk for NiV infection among persons who had contact with a potential intermediate host. Although we cannot rule out person-to-person transmission, case-patients were likely infected from contact with fruit bats or their secretions.
• Subjects:
  Adolescent Adult Animals Case-Control Studies Child Child, Preschool Chiroptera Disease Vectors Encephalitis, Viral Female Henipavirus Infections Humans Male Nipah Virus Odds Ratio Research Risk Factors

  More +
• Source:
  Emerg Infect Dis. 14(10):1526-1532
• Pubmed ID:
  18826814
• Pubmed Central ID:
  PMC2609878
• Document Type:
  Journal Article
• Place as Subject:
  Bangladesh
• Location:
  Asia
• Volume:
  14
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:57231a3d7d7fe7d8ca7602f88444c4e0e6a2c89021875ae0fd6ddc135ce29366
• Download URL:
  https://stacks.cdc.gov/view/cdc/3159/cdc_3159_DS1.pdf
• File Type:
  [PDF - 172.63 KB ]