Neonatal jaundice in association with autism spectrum disorder and developmental disorder

Details

• Journal Article:
  J Perinatol
• Personal Author:
  Cordero, Christina ; Schieve, Laura A. ; Croen, Lisa A. ; Engel, Stephanie M. ; Siega-Riz, Anna Maria ; Herring, Amy H. ; Vladutiu, Catherine J. ; Seashore, Carl J. ; Daniels, Julie L.
• Description:
  Objective ; To examine the association between neonatal jaundice and autism spectrum disorder (ASD) and non-ASD developmental disorder (DD). ; Study design ; We analyzed data from the Study to Explore Early Development, a US multisite, case-control study conducted from 2007 to 2011. Developmental assessment classified children aged 2–5 years into: ASD (n= 636), DD (n= 777), or controls (POP; n= 926). Neonatal jaundice (n= 1054) was identified from medical records and maternal interviews. We examined associations between neonatal jaundice and ASD and DD using regression models to obtain adjusted odds ratios (aOR). ; Results ; Our results showed interaction between gestational age and neonatal jaundice. Neonatal jaundice was associated with ASD at 35–37 weeks (aOR = 1.83, 95%CI 1.05, 3.19), but not ≥38 weeks gestation (aOR = 0.97, 95%CI 0.76, 1.24). Similar results were observed with DD. ; Conclusions ; Further exploration of timing and severity of neonatal jaundice and ASD/DD is warranted.
• Keywords:
  • Adult
  • Age Factors
  • Autism Spectrum Disorder
  • Case-Control Studies
  • Child, Preschool
  • Developmental Disabilities
  • Female
  • Gestational Age
  • Humans
  • Infant, Premature
  More +
• Source:
  J Perinatol. 40(2):219-225
• DOI:
  http://dx.doi.org/10.1038/s41372-019-0452-4
• Pubmed ID:
  31388117
• Pubmed Central ID:
  PMC7031756
• Document Type:
  Text ; Journal Article
• Funding:
  T32 HD052468/HD/NICHD NIH HHSUnited States/ ; U10 DD000181/DD/NCBDD CDC HHSUnited States/ ; U10 DD000184/DD/NCBDD CDC HHSUnited States/ ; U01 DD000498/DD/NCBDD CDC HHSUnited States/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/ ; U01 DD000750/DD/NCBDD CDC HHSUnited States/ ; U10 DD000182/DD/NCBDD CDC HHSUnited States/ ; U01DD000750/ACL/ACL HHSUnited States/ ; U10 DD000183/DD/NCBDD CDC HHSUnited States/ ; P30 ES010126/ES/NIEHS NIH HHSUnited States/ ; U10 DD000180/DD/NCBDD CDC HHSUnited States/
  More +
• Genre:
  Journal Article
• Volume:
  40
• Issue:
  2
• Download URL:
  https://stacks.cdc.gov/view/cdc/85255/cdc_85255_DS1.pdf
• File Type:
  [PDF - 422.74 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:16469a37299b473ebb5c0afde7ff8e8344e8c29a5f86b6ce29f55188a7d0e4823e9fd290975259004dc04de10551b48cd65281afd442ec16a1845b581e76bf22