KPC and NDM-1 Genes in Related Enterobacteriaceae Strains and Plasmids from Pakistan and the United States

Pesesky, Mitchell W.; Hussain, Tahir; Wallace, Meghan; Wang, Bin; Andleeb, Saadia; Burnham, Carey-Ann D.; Dantas, Gautam

doi:10.3201/eid2106.141504

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KPC and NDM-1 Genes in Related Enterobacteriaceae Strains and Plasmids from Pakistan and the United States

Jun 2015
By Pesesky, Mitchell W. ; Hussain, Tahir ; Wallace, Meghan ; ...
http://dx.doi.org/10.3201/eid2106.141504
Source: Emerg Infect Dis. 21(6):1034-1037.

[PDF-3.18 MB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Pesesky, Mitchell W. ; Hussain, Tahir ; Wallace, Meghan ; Wang, Bin ; Andleeb, Saadia ; ... More +

Pesesky, Mitchell W. ; Hussain, Tahir ; Wallace, Meghan ; Wang, Bin ; Andleeb, Saadia ; Burnham, Carey-Ann D. ; Dantas, Gautam Less -
Description:

To characterize the genomic context of New Delhi metallo-β-lactamase-1 (NDM-1) and Klebsiella pneumoniae carbapenemase (KPC), we sequenced 78 Enterobacteriaceae isolates from Pakistan and the United States encoding KPC, NDM-1, or no carbapenemase. High similarities of the results indicate rapid spread of carbapenem resistance between strains, including globally disseminated pathogens.
Subjects:

[+]

Anti-Bacterial Agents/pharmacology Bacterial Proteins/genetics Beta-Lactamases/genetics Beta-Lactam Resistance Carbapenems/pharmacology Computational Biology/methods Dispatch Enterobacteriaceae Enterobacteriaceae Infections Genomics/methods Humans Microbial Sensitivity Tests Plasmids
Source:

Emerg Infect Dis. 21(6):1034-1037.
Document Type:

Journal Article
Funding:

DP2DK098089/DK/NIDDK NIH HHS/United States ; GM:007067/GM/NIGMS NIH HHS/United States ; R01GM099538/GM/NIGMS NIH HHS/United States

DP2DK098089/DK/NIDDK NIH HHS/United States ; GM:007067/GM/NIGMS NIH HHS/United States ; R01GM099538/GM/NIGMS NIH HHS/United States Less -
Place as Subject:

Pakistan ; United States

Pakistan ; United States Less -
Location:

Asia ; North America

Asia ; North America Less -
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:ea9ec79d9cd90eb009af53ad3bd112cb0e659beb2cc74610557bb6a7065e2171
Download URL:

https://stacks.cdc.gov/view/cdc/31455/cdc_31455_DS1.pdf
File Type:

	license.txt	txt
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	14-1504-F1.jpg	jpeg
	14-1504-F2.gif	gif
	14-1504-F2.jpg	jpeg
	14-1504-Techapp-s1.pdf	pdf
	14-1504.nxml	txt

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