Occupational Determinants of Cumulative Lead Exposure: Analysis of Bone Lead Among Men in the VA Normative Aging Study

Ji, John S.; Schwartz, Joel; Sparrow, David; Hu, Howard; Weisskopf, Marc G.

doi:10.1097/JOM.0000000000000127

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Occupational Determinants of Cumulative Lead Exposure: Analysis of Bone Lead Among Men in the VA Normative Aging Study

Published Date:

Apr 2014

Publisher's site:

http://dx.doi.org/10.1097/JOM.0000000000000127 New Site Icon

Source:

J Occup Environ Med. 56(4):435-440.

[PDF - 232.03 KB]

Details:

Personal Authors:

Ji, John S. ; Schwartz, Joel ; Sparrow, David ; Hu, Howard ; Weisskopf, Marc G. ;

Keywords:

[+]

Pubmed ID:

24709766

Pubmed Central ID:

PMC3982188

Description:

Objectives

To examine the relation between occupation and cumulative lead exposure—assessed by measuring bone lead—in a community-dwelling population

Method

We measured bone lead concentration with K-shell X-Ray Fluorescence in 1,320 men in the Normative Aging Study. We categorized job titles into 14 broad US Census Bureau categories. We used ordinary least squares regression to estimate bone lead by job categories adjusted for other predictors.

Results

Service Workers, Construction and Extractive Craft Workers, and Installation, Maintenance and Repair Craft Workers had the highest bone lead concentrations. Including occupations significantly improved the overall model (p<0.001) and reduced by −15% to −81% the association between bone lead and education categories.

Conclusion

Occupation significantly predicts cumulative lead exposure in a community-dwelling population, and accounts for a large proportion of the association between education and bone lead.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

P30 ES000002/ES/NIEHS NIH HHS/United States
R01 ES005257/ES/NIEHS NIH HHS/United States
T42/OH008416/OH/NIOSH CDC HHS/United States

Supporting Files:

NIHMS558244-supplement-Supplemental_Digital_Content.docx	application/vnd.openxmlformats-officedocument.wordprocessingml.document
nihms558244.nxml	text/plain

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