Details:

Alternative Title:
Opt Lett
Personal Author:
Zhou, Yong ; Yao, Junjie ; Wang, Lihong V. ;
Zhou, Yong ; Yao, Junjie ; Wang, Lihong V. ; Less -
Description:
Due to strong light scattering in tissue, both the spatial resolution and maximum penetration depth of optical-resolution photoacoustic microscopy (OR-PAM) deteriorate sharply with depth. To reduce tissue scattering, we propose to use glycerol as an optical clearing agent in OR-PAM. Our results show that the imaging performance of OR-PAM can be greatly enhanced by optical clearing both in vitro and in vivo.
Subject:
[+]
Animals
Article
Epidermis
Image Processing, Computer-Assisted
Mice
Microscopy
Optical Phenomena
Phantoms, Imaging
Photoacoustic Techniques
Signal-To-Noise Ratio

Source:
Opt Lett. 2013 ; 38(14):2592-2595.;
Pubmed ID:
23939121
Pubmed Central ID:
PMC3759812
Document Type:
Journal Article ;
Funding:
T32 EB014855/EB/NIBIB NIH HHS/United States ; R01 CA134539/CA/NCI NIH HHS/United States ; R01 CA157277/CA/NCI NIH HHS/United States ; U54 CA136398/CA/NCI NIH HHS/United States ; R01 CA159959/CA/NCI NIH HHS/United States ; ... More +
T32 EB014855/EB/NIBIB NIH HHS/United States ; R01 CA134539/CA/NCI NIH HHS/United States ; R01 CA157277/CA/NCI NIH HHS/United States ; U54 CA136398/CA/NCI NIH HHS/United States ; R01 CA159959/CA/NCI NIH HHS/United States ; DP1 EB016986/EB/NIBIB NIH HHS/United States ; R01 EB008085/EB/NIBIB NIH HHS/United States ; DP1 EB016986/DP/NCCDPHP CDC HHS/United States ; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:036828e61a4153f8427de792c7306810594ccbdf0c9aefdc92c8ee3d83e6f5ce
File Type:

Supporting Files

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