Details:

Alternative Title:
Nat Neurosci
Personal Author:
Froudarakis, Emmanouil ; Berens, Philipp ; Ecker, Alexander S. ; Cotton, R. James ; Sinz, Fabian H. ; ... More +
Froudarakis, Emmanouil ; Berens, Philipp ; Ecker, Alexander S. ; Cotton, R. James ; Sinz, Fabian H. ; Yatsenko, Dimitri ; Saggau, Peter ; Bethge, Matthias ; Tolias, Andreas S. Less -
Description:
Neural codes are believed to have adapted to the statistical properties of the natural environment. However, the principles that govern the organization of ensemble activity in the visual cortex during natural visual input are unknown. We recorded populations of up to 500 neurons in the mouse primary visual cortex and characterized the structure of their activity, comparing responses to natural movies with those to control stimuli. We found that higher order correlations in natural scenes induced a sparser code, in which information is encoded by reliable activation of a smaller set of neurons and can be read out more easily. This computationally advantageous encoding for natural scenes was state-dependent and apparent only in anesthetized and active awake animals, but not during quiet wakefulness. Our results argue for a functional benefit of sparsification that could be a general principle governing the structure of the population activity throughout cortical microcircuits.
Subject:
[+]
Action Potentials
Animals
Article
Female
Male
Mice
Mice, Inbred C57BL
Nerve Net
Photic Stimulation
Visual Cortex
Visual Perception
Wakefulness

Source:
Nat Neurosci. 17(6):851-857.
Pubmed ID:
24747577
Pubmed Central ID:
PMC4106281
Document Type:
Journal Article
Funding:
DP1 EY023176/EY/NEI NIH HHS/United States ; DP1-OD008301/OD/NIH HHS/United States ; NEI DP1-EY023176/DP/NCCDPHP CDC HHS/United States ; NEI P30-EY002520/EY/NEI NIH HHS/United States ; NIDA RO1-DA028525/PHS HHS/United States ; ... More +
DP1 EY023176/EY/NEI NIH HHS/United States ; DP1-OD008301/OD/NIH HHS/United States ; NEI DP1-EY023176/DP/NCCDPHP CDC HHS/United States ; NEI P30-EY002520/EY/NEI NIH HHS/United States ; NIDA RO1-DA028525/PHS HHS/United States ; P30 EY002520/EY/NEI NIH HHS/United States ; R01 EY018847/EY/NEI NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:54e149710abe4afb445860aee445ceebd9e821c601ff324b3a6ef57886d84d13
File Type:

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