Oseltamivir-Resistant Influenza A(H1N1)pdm09 Viruses, United States, 2013–14

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Okomo-Adhiambo, Margaret ; Fry, Alicia M. ; Su, Su ; Nguyen, Ha T. ; Elal, Anwar Abd ; Negron, Elizabeth ; Hand, Julie ; Garten, Rebecca J. ; Barnes, John ; Xiyan, Xu ; Villanueva, Julie M. ; Gubareva, Larisa V.
• Corporate Authors:
  2013–14 US Influenza Antiviral Working Group
• Description:
  We report characteristics of oseltamivir-resistant influenza A(H1N1)pdm09 viruses and patients infected with these viruses in the United States. During 2013-14, fifty-nine (1.2%) of 4,968 analyzed US influenza A(H1N1)pdm09 viruses had the H275Y oseltamivir resistance-conferring neuraminidase substitution. Our results emphasize the need for local surveillance for neuraminidase inhibitor susceptibility among circulating influenza viruses.
• Subjects:
  Adolescent Adult Antiviral Agents Dispatch Drug Resistance, Viral Female Humans Influenza, Human Influenza A Virus, H1N1 Subtype Male Middle Aged Neuraminidase Oseltamivir Phylogeny Prevalence Viral Proteins Young Adult

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• Source:
  Emerg Infect Dis. 21(1):136-141.
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Location:
  North America
• Volume:
  21
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:046327a940bc7518844385bb2030bf79defb29163995172619220327b9f785e0
• Download URL:
  https://stacks.cdc.gov/view/cdc/26689/cdc_26689_DS1.pdf
• File Type:
  [PDF - 568.64 KB ]