Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020

Mohan, Teena; Nguyen, Ha T.; Kniss, Krista; Mishin, Vasiliy P.; Merced-Morales, Angiezel A.; Laplante, Jennifer; St. George, Kirsten; Blevins, Patricia; Chesnokov, Anton; De La Cruz, Juan A.; Kondor, Rebecca; Wentworth, David E.; Gubareva, Larisa V.

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Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020

Supporting Files Public Domain

July 2021
By Mohan, Teena ; Nguyen, Ha T. ; Kniss, Krista ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Mohan, Teena ; Nguyen, Ha T. ; Kniss, Krista ; Mishin, Vasiliy P. ; Merced-Morales, Angiezel A. ; Laplante, Jennifer ; St. George, Kirsten ; Blevins, Patricia ; Chesnokov, Anton ; De La Cruz, Juan A. ; Kondor, Rebecca ; Wentworth, David E. ; Gubareva, Larisa V.
Description:

Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the necessity to monitor both drug resistance and antigenic drift of circulating viruses.
Subjects:

Antiviral Agents Drug Resistance, Viral Hemagglutinins Humans Influenza, Human Influenza A Virus, H1N1 Subtype Neuraminidase Oseltamivir Viral Proteins
Source:

Emerg Infect Dis. 27(7):1953-1957
Pubmed ID:

34152954
Pubmed Central ID:

PMC8237887
Document Type:

Journal Article
Place as Subject:

Texas
Location:

North America
Volume:

27
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:b96f9a6c2208c6ca73f7ed7c852cc86a341b66bc253e6a4a780acda3b4019995
Download URL:

https://stacks.cdc.gov/view/cdc/107962/cdc_107962_DS1.pdf
File Type:

[PDF - 1.17 MB ]

File Language:

English

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