Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Booth, Malcolm ; Donaldson, Lindsay ; Cui, Xizhong ; Sun, Junfeng ; Cole, Stephen ; ... More +
Booth, Malcolm ; Donaldson, Lindsay ; Cui, Xizhong ; Sun, Junfeng ; Cole, Stephen ; Dailsey, Susan ; Hart, Andrew ; Johns, Neil ; McConnell, Paul ; McLennan, Tina ; Parcell, Benjamin ; Robb, Henry ; Shippey, Benjamin ; Sim, Malcolm ; Wallis, Charles ; Eichacker, Peter Q. Less -
Description:
Patients who died had an increased sequential organ failure assessment score and need for vasopressors.|In Scotland, the 2009 outbreak of | infection among persons who inject drugs resulted in a 28% death rate. To compare nonsurvivors and survivors, we obtained data on 11 nonsurvivors and 16 survivors. Time from | exposure to symptoms or hospitalization and skin and limb findings at presentation did not differ between nonsurvivors and survivors. Proportionately more nonsurvivors had histories of excessive alcohol use (p = 0.05) and required vasopressors and/or mechanical ventilation (p|0.01 for each individually). Nonsurvivors also had higher sequential organ failure assessment scores (mean | SEM) (7.3 | 0.9 vs. 1.2 | 0.4, p<0.0001). Antibacterial drug administration, surgery, and anthrax polyclonal immune globulin treatments did not differ between nonsurvivors and survivors. Of the 14 patients who required vasopressors during hospitalization, 11 died. Sequential organ failure assessment score or vasopressor requirement during hospitalization might identify patients with injectional anthrax for whom limited adjunctive therapies might be beneficial.
Subjects:
[+]
Adult Anthrax/Diagnosis Anthrax/Drug Therapy Anthrax/Epidemiology Anthrax/History Anthrax/Transmission Bacillus Anthracis Disease Outbreaks Drug Users History, 21St Century Humans Immune Sera Public Health Surveillance Risk Factors Vasoconstrictor Agents
Source:
Emerg Infect Dis. 20(9):1452-1463.
Document Type:
Journal Article
Place as Subject:
Scotland
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:0a388fead6df42d911a42ba300e5e3262f99770e68a266d31c7b3688c8ecb7d6
Download URL:
https://stacks.cdc.gov/view/cdc/25473/cdc_25473_DS1.pdf
File Type:

Supporting Files

• 	13-1481-FINAL_medscape.nxml	txt
  	license.txt	txt
  	13-1481-F1.gif	gif
  	13-1481-F1.jpg	jpeg
  	13-1481-F2.gif	gif
  	13-1481-F2.jpg	jpeg
  	13-1481-F3.gif	gif
  	13-1481-F3.jpg	jpeg
  	13-1481-F4.gif	gif
  	13-1481-F4.jpg	jpeg

More +