Biological effects of crude oil vapor. IV. Cardiovascular effects (dataset).

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  According to the North American Industry Classification System, workers employed in the oil and gas extraction industry are working in one of three areas; 1) extraction, 2) drilling, or 3) processing and refinement (Bureau of Labor Statistics, April 15, 2014). Both workers and people living in communities that are in close proximity to areas where gas and oil extraction and refinement occur have a higher incidence of respiratory, cardiovascular, digestive, reproductive and nervous system disorders, The goal of these studies was to identify mechanisms underlying the development of cardiovascular disease after inhalation of crude oil vapors (COV). The oil used for this study was a surrogate of the crude oil that leaked into the Gulf of Mexico after the Deepwater Horizon oil spill (McKinney et al., 2021). We tested the hypothesis that changes in cardiovascular function after inhalation of COV are manifested as changes in the responsiveness of the heart and peripheral vascular system to vasoconstricting and vasodilating agonists. Based on previous studies, we also predicted that inhalation of COV would affect the expression of biomarkers of cardiac and kidney function that are associated with blood pressure regulation and disease. [Description provided by NIOSH]
• Subjects:
  Cardiovascular Diseases Cardiovascular System Occupational Health Oil And Gas Industry Respiratory System Safety
• Keywords:
  Oil vapors; Oil industry; Gas industry; Cardiovascular disease; Crude oil; Oil spills; Deepwater Horizon; Inhalation; Cardiac function; Kidney function
• DOI:
  https://doi.org/10.26616/NIOSHRD-1038-2022-0
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Dataset
• Genre:
  Research Dataset
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:20065351
• Citation:
  Morgantown, WV: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Research Dataset RD-1038-2022-0, 2022 Jun; :dataset
• Contact Point Address:
  Physical Effects Research Branch, Health Effects Laboratory Division, NIOSH Morgantown, WV. Phone: 304-285-6230
• Federal Fiscal Year:
  2022
• NORA Priority Area:
  Oil and Gas Extraction
• Peer Reviewed:
  False
• Source Full Name:
  Biological effects of crude oil vapor. IV. Cardiovascular effects
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:dc0d84ed7ae08c47d837e98e3a6fc8593311aa9dccc939727e178c8c81dad1df8f4c00daff47b4748490068076acee4e2f6a0187a648a76fbdf2e70d84975381
• Download URL:
  https://stacks.cdc.gov/view/cdc/248778/cdc_248778_DS1.pdf
• File Type:
  [PDF - 529.56 KB ]