Travel-related Dengue Virus Infection, the Netherlands, 2006–2007

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Baaten, Gijs G.G. ; Sonder, Gerard J.B. ; Zaaijer, Hans L. ; van Gool, Tom ; Kint, Joan A.P.C.M. ; van den Hoek, Anneke
• Description:
  To assess the incidence of and risk factors for clinical and subclinical dengue virus (DENV) infection, we prospectively studied 1,207 adult short-term travelers from the Netherlands to dengue-endemic areas. Participants donated blood samples for serologic testing before and after travel. Blood samples were tested for antibodies against DENV. Seroconversion occurred in 14 (1.2%) travelers at risk. The incidence rate was 14.6 per 1,000 person-months. The incidence rate was significantly higher for travel during the rainy months. Dengue-like illness occurred in 5 of the 14 travelers who seroconverted. Seroconversion was significantly related to fever, retro-orbital pain, myalgia, arthralgia, and skin rash. The risk for DENV infection for short-term travelers to dengue-endemic areas is substantial. The incidence rate for this study is comparable with that in 2 other serology-based prospective studies conducted in the 1990s.
• Subjects:
  Adult Antibodies, Viral Dengue Dengue Virus Epidemiology Female Humans Incidence Male Middle Aged Netherlands Prevalence Prospective Studies Prospective Study Research Risk Factors Serologic Tests The Netherlands Travel Travelers Vector-borne Infections Viruses

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• Source:
  Emerg Infect Dis. 17(5):821-828.
• Document Type:
  Journal Article
• Volume:
  17
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha-512:3ce388a24dc511b6c1e4064159f3247969022801e0ca9f59272e6ffd673f5179843a21a4dd612e7b1842d6a5e095af9d459935e2336b906a74791764b35df72a
• Download URL:
  https://stacks.cdc.gov/view/cdc/24351/cdc_24351_DS1.pdf
• File Type:
  [PDF - 226.93 KB ]