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Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
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Details:
  • Pubmed ID:
    24513728
  • Pubmed Central ID:
    PMC4091281
  • Description:
    Biomarkers are directly-measured biological indicators of disease, health, exposures, or other biological information. In population and social sciences, biomarkers need to be easy to obtain, transport, and analyze. Dried Blood Spots meet this need, and can be collected in the field with high response rates. These elements are particularly important in longitudinal study designs including interventions where attrition is critical to avoid, and high response rates improve the interpretation of results. Dried Blood Spot sample collection is simple, quick, relatively painless, less invasive then venipuncture, and requires minimal field storage requirements (i.e. samples do not need to be immediately frozen and can be stored for a long period of time in a stable freezer environment before assay). The samples can be analyzed for a variety of different analytes, including cholesterol, C-reactive protein, glycosylated hemoglobin, numerous cytokines, and other analytes, as well as provide genetic material. DBS collection is depicted as employed in several recent studies.

  • Document Type:
  • Collection(s):
  • Funding:
    R01HL107240/HL/NHLBI NIH HHS/United States
    U01AG027669/AG/NIA NIH HHS/United States
    U01HD051217/HD/NICHD NIH HHS/United States
    U01HD051218/HD/NICHD NIH HHS/United States
    U01HD051256/HD/NICHD NIH HHS/United States
    U01HD051276/HD/NICHD NIH HHS/United States
    U01HD059773/HD/NICHD NIH HHS/United States
    U01OH008788/OH/NIOSH CDC HHS/United States
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