NIOSH testimony on formaldehyde by R. A. Lemen, May 5, 1986.

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  In view of animal studies indicating that formaldehyde (50000) was a carcinogen, this testimony provided evidence to support the position that exposure to formaldehyde be kept to the lowest feasible concentration possible; 0.1 part per million (ppm) in air by collection of an air sample for any 15 minute period, the lowest quantifiable detected concentration at the present time. Significant excesses of squamous cell carcinomas of the nasal cavity were found in both male and female Fischer-344-rats, in male hybrid- mice, and in male Sprague-Dawley-rats. Results of individual studies suggested a connection between formaldehyde exposure and the incidence of lung cancer, brain cancer, leukemia, and nasopharyngeal cancer. The mutagenicity of formaldehyde was demonstrated in studies on fruit-flies, grasshoppers, flowering plants, fungi, and bacteria. Evidence suggested that formaldehyde forms cross linking bonds between DNA and protein at concentrations of 6ppm and greater. Examination of workplace exposure data suggested that in most occupations formaldehyde exposures were below 0.5ppm concentration levels with only 10 percent being above 1ppm. Problems encountered using particular monitoring and respiratory protective equipment were briefly considered. [Description provided by NIOSH]
• Content Notes:
  in NTRL, no PDF
• Subjects:
  Carcinogens Mutagens Neoplasms Nose Nose Diseases Occupational Health Risk Assessment Safety Sense Organs Textile Industry
• Keywords:
  NIOSH-Author; NIOSH-Testimony; Lemen-R-A; Garment-workers; Risk-analysis; Cancer-rates; Nasal-cancer; Carcinogens; Mutagens
• Document Type:
  Text
• Genre:
  Testimony
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-17
• NIOSHTIC Number:
  nn:00170021
• NTIS Accession Number:
  PB87222626
• Citation:
  NIOSH 1986 May; :1-17
• CAS Registry Number:
  Formaldehyde (CAS RN 50-00-0)
• Federal Fiscal Year:
  1986
• Peer Reviewed:
  False
• Source Full Name:
  NIOSH, 17 pages
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/242247/cdc_242247_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]