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Fatal Neurologic Disease and Abortion in Mare Infected with Lineage 1 West Nile Virus, South Africa
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  1. West Nile Virus Lineage 2 in Horses and Other Animals with Neurologic Disease, South Africa, 2008–2015
    Personal Author:
    Venter, Marietjie; Pretorius, Marthi; Fuller, James A.; Botha, Elizabeth; Rakgotho, Mpho; Stivaktas, Voula; Weyer, Camilla; Romito, Marco; Williams, June;
    Published Date:
    Dec 2017
    Source:
    Emerg Infect Dis. 23(12):2060-2064.
    Description:
    During 2008-2015 in South Africa, we conducted West Nile virus surveillance in 1,407 animals with neurologic disease and identified mostly lineage 2 cases in horses (7.4%, 79/1,069), livestock (1.5%, 2/132), and wildlife (0.5%, 1/206); 35% were fatal...
    File Type:
    Filetype[PDF - 1.03 MB]
  2. West Nile Virus in Wildlife and Nonequine Domestic Animals, South Africa, 2010–2018
    Personal Author:
    Steyn, Jumari; Botha, Elizabeth; Stivaktas, Voula I.; Buss, Peter; Beechler, Brianna R.; Myburgh, Jan G.; Steyl, Johan; Williams, June; Venter, Marietjie;
    Published Date:
    December 2019
    Source:
    Emerg Infect Dis. 25(12):2290-2294
    Description:
    West Nile virus (WNV) lineage 2 is associated with neurologic disease in horses and humans in South Africa. Surveillance in wildlife and nonequine domestic species during 2010-2018 identified WNV in 11 (1.8%) of 608 animals with severe neurologic and...
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  3. Lineage 2 West Nile Virus as Cause of Fatal Neurologic Disease in Horses, South Africa
    Personal Author:
    Venter, Marietjie; Human, Stacey; Zaayman, Dewald; Gerdes, Gertruida H.; Williams, June; Steyl, Johan; Leman, Patricia A.; Paweska, Janusz Tadeusz; Setzkorn, Hildegard; Rous, Gavin; Murray, Sue; Parker, Rissa; Donnellan, Cynthia; Swanepoel, Robert;
    Published Date:
    Jun 2009
    Source:
    Emerg Infect Dis. 15(6):877-884.
    Description:
    Serologic evidence suggests that West Nile virus (WNV) is widely distributed in horses in southern Africa. However, because few neurologic cases have been reported, endemic lineage 2 strains were postulated to be nonpathogenic in horses. Recent evide...
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  4. Sindbis and Middelburg Old World Alphaviruses Associated with Neurologic Disease in Horses, South Africa
    Personal Author:
    van Niekerk, Stephanie; Human, Stacey; Williams, June; van Wilpe, Erna; Pretorius, Marthi; Swanepoel, Robert; Venter, Marietjie;
    Published Date:
    Dec 2015
    Source:
    Emerg Infect Dis. 21(12):2225-2229
    Description:
    Old World alphaviruses were identified in 52 of 623 horses with febrile or neurologic disease in South Africa. Five of 8 Sindbis virus infections were mild; 2 of 3 fatal cases involved co-infections. Of 44 Middelburg virus infections, 28 caused neuro...
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  5. Full-Genome Sequence of a Neuroinvasive West Nile Virus Lineage 2 Strain from a Fatal Horse Infection in South Africa
    Personal Author:
    Mentoor, Juliet L. D.; Lubisi, Alison B.; Gerdes, Truuska; Human, Stacey; Williams, June H.; Venter, Marietjie;
    Published Date:
    Jul 28 2016
    Source:
    Genome Announc. 2016; 4(4).
    Description:
    We report here the complete genome sequence of a lineage 2 West Nile virus (WNV) strain that resulted in fatal neurological disease in a horse in South Africa. Several recent reports exist of neurological disease associated with lineage 2 WNV in huma...
    File Type:
    Filetype[PDF - 142.67 KB]