Epidemiology of Influenza Virus Types and Subtypes in South Africa, 2009–20121

Cohen, Adam L.; Hellferscee, Orienka; Pretorius, Marthi; Treurnicht, Florette; Walaza, Sibongile; Madhi, Shabir; Groome, Michelle; Dawood, Halima; Variava, Ebrahim; Kahn, Kathleen; Wolter, Nicole; von Gottberg, Anne; Tempia, Stefano; Venter, Marietjie; Cohen, Cheryl

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Epidemiology of Influenza Virus Types and Subtypes in South Africa, 2009–20121

Supporting Files Public Domain

Jul 2014
By Cohen, Adam L. ; Hellferscee, Orienka ; Pretorius, Marthi ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Cohen, Adam L. ; Hellferscee, Orienka ; Pretorius, Marthi ; Treurnicht, Florette ; Walaza, Sibongile ; Madhi, Shabir ; Groome, Michelle ; Dawood, Halima ; Variava, Ebrahim ; Kahn, Kathleen ; Wolter, Nicole ; von Gottberg, Anne ; Tempia, Stefano ; Venter, Marietjie ; Cohen, Cheryl
Description:

To determine clinical and epidemiologic differences between influenza caused by different virus types and subtypes, we identified patients and tested specimens. Patients were children and adults hospitalized with confirmed influenza and severe acute respiratory illness (SARI) identified through active, prospective, hospital-based surveillance from 2009-2012 in South Africa. Respiratory specimens were tested, typed, and subtyped for influenza virus by PCR. Of 16,005 SARI patients tested, 1,239 (8%) were positive for influenza virus. Patient age and co-infections varied according to virus type and subtype, but disease severity did not. Case-patients with influenza B were more likely than patients with influenza A to be HIV infected. A higher proportion of case-patients infected during the first wave of the 2009 influenza pandemic were 5-24 years of age (19%) than were patients infected during the second wave (9%). Although clinical differences exist, treatment recommendations do not differ according to subtype; prevention through vaccination is recommended.
Subjects:

Adult Aged Aolescent Child Child, Preschool Coinfection Female Humans Influenza, Human Influenza A Virus Influenza B Virus Male Middle Aged Prospective Studies Research Young Adult
Source:

Emerg Infect Dis. 20(7):1149-1156.
Document Type:

Journal Article
Place as Subject:

South Africa
Location:

Africa
Volume:

20
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:d1eee5d336645e0b9c20df0088050c9c2df17ba217b7c27685fe679c61696685
Download URL:

https://stacks.cdc.gov/view/cdc/24113/cdc_24113_DS1.pdf
File Type:

[PDF - 545.52 KB ]

File Language:

English

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