Details:

Alternative Title:
PLoS One
Personal Author:
Feng, Luzhao ; Li, Zhongjie ; Zhao, Shiwen ; Nair, Harish ; Lai, Shengjie ; ... More +
Feng, Luzhao ; Li, Zhongjie ; Zhao, Shiwen ; Nair, Harish ; Lai, Shengjie ; Xu, Wenbo ; Li, Mengfeng ; Wu, Jianguo ; Ren, Lili ; Liu, Wei ; Yuan, Zhenghong ; Chen, Yu ; Wang, Xinhua ; Zhao, Zhuo ; Zhang, Honglong ; Li, Fu ; Ye, Xianfei ; Li, Sa ; Feikin, Daniel ; Yu, Hongjie ; Yang, Weizhong Less -
Description:
Background

Acute lower respiratory infections (ALRIs) are an important cause of acute illnesses and mortality worldwide and in China. However, a large-scale study on the prevalence of viral infections across multiple provinces and seasons has not been previously reported from China. Here, we aimed to identify the viral etiologies associated with ALRIs from 22 Chinese provinces.

Methods and Findings

Active surveillance for hospitalized ALRI patients in 108 sentinel hospitals in 24 provinces of China was conducted from January 2009-September 2013. We enrolled hospitalized all-age patients with ALRI, and collected respiratory specimens, blood or serum collected for diagnostic testing for respiratory syncytial virus (RSV), human influenza virus, adenoviruses (ADV), human parainfluenza virus (PIV), human metapneumovirus (hMPV), human coronavirus (hCoV) and human bocavirus (hBoV).

Conclusions

Our findings could serve as robust evidence for public health authorities in drawing up further plans to prevent and control ALRIs associated with viral pathogens. RSV is common in young children and prevention measures could have large public health impact. Influenza was most common in adults and influenza vaccination should be implemented on a wider scale in China.


Subjects:
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Adenoviridae Adolescent Adult Aged Bocavirus Child Child, Preschool Coronavirus Female Humans Infant Male Metapneumovirus Middle Aged Orthomyxoviridae Paramyxoviridae Infections Respiratory Syncytial Virus Infections Respiratory Tract Infections Seasons
Source:
PLoS One. 2014; 9(6).
Document Type:
Journal Article
Place as Subject:
China
Collection(s):
CDC Public Access
Main Document Checksum:
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urn:sha256:45d7f7a56c6e518d8b2af07c86e83e50fdd8b62ce2c40b13416f9b80584d0e58
Download URL:
https://stacks.cdc.gov/view/cdc/23949/cdc_23949_DS1.pdf
File Type:

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