i
High Prevalence of Multidrug-Resistant Tuberculosis, Swaziland, 2009–2010
-
Jan 2012
-
-
Source: Emerg Infect Dis. 18(1):29-37.
Details:
-
Alternative Title:Emerg Infect Dis
-
Personal Author:
-
Description:In Africa, although emergence of multidrug-resistant (MDR) tuberculosis (TB) represents a serious threat in countries severely affected by the HIV epidemic, most countries lack drug-resistant TB data. This finding was particularly true in the Kingdom of Swaziland, which has the world's highest HIV and TB prevalences. Therefore, we conducted a national survey in 2009-2010 to measure prevalence of drug-resistant TB. Of 988 patients screened, 420 new case-patients and 420 previously treated case-patients met the study criteria. Among culture-positive patients, 15.3% new case-patients and 49.5% previously treated case-patients harbored drug-resistant strains. MDR TB prevalence was 7.7% and 33.8% among new case-patients and previously treated case-patients, respectively. HIV infection and past TB treatment were independently associated with MDR TB. The findings assert the need for wide-scale intervention in resource-limited contexts such as Swaziland, where diagnostic and treatment facilities and health personnel are lacking.
-
Subjects:
-
Source:
-
Document Type:
-
Place as Subject:
-
Location:
-
Volume:18
-
Issue:1
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type: