Association of Rheumatoid Arthritis with Opioid Pain Medication Overuse Among Persons Exposed to the 9/11 World Trade Center Disaster

Details

• Personal Author:
  Cone, James E. ; Dhanya AS ; Li J ; Yung J
• Description:
  We examined the association of post-9/11 rheumatoid arthritis (RA) diagnosis with opioid pain medication overuse among enrollees in the World Trade Center Health Registry (WTCHR). Opioid overuse was defined as the self-reported intake of prescribed opioids at a higher dosage or more often than directed in the last 12 months on one of the two most recent WTCHR surveys (2015-2016, 2020-2021). Post-9/11 RA was ascertained through self-reports and subsequently validated following medical record release by the enrollees' physicians or medical records review. We excluded those with self-reported RA that was not validated by their physicians and those who did not report being prescribed opioid pain medication in the last 12 months. Multivariable log-binomial regression was conducted to examine the relationship between post-9/11 RA diagnosis and opioid pain medication overuse, adjusting for sociodemographic characteristics and 9/11-related posttraumatic stress disorder (PTSD) symptoms. Of the 10,196 study enrollees, 46 had confirmed post-9/11 RA. The post-9/11 RA patients were mostly females (69.6% vs. 37.7%), less frequently non-Hispanic White (58.7% vs. 73.2%) individuals, and less often had attained a higher level of education (76.1% vs. 84.4%) compared to those without post-9/11 RA. Opioid pain medication overuse was significantly associated with a post-9/11 RA diagnosis (Adjusted Risk Ratio: 2.13, 95% CI: 1.44-3.17). More research is needed to better understand the use and management of prescribed opioids among WTC-exposed individuals with RA. [Description provided by NIOSH]
• Subjects:
  Demography Occupational Health Safety September 11 Terrorist Attacks
• Keywords:
  Author Keywords: World Trade Center (WTC) Disaster Demographic Characteristics Medical Records Medicinal Chemicals Opioids Pain Medication Post-traumatic Stress Disorder Posttraumatic Stress Disorder (PTSD) PTSD Rheumatoid Arthritis Rheumatoid Disorders Sociological Factors World Trade Center WTC

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• ISSN:
  1660-4601
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  20
• Issue:
  5
• NIOSHTIC Number:
  nn:20067098
• Citation:
  Int J Environ Res Public Health 2023 Feb; 20(5):4166
• Contact Point Address:
  Janette Yung, New York City Department of Health and Mental Hygiene, World Trade Center Health Registry, Long Island City, NY 11101
• Email:
  jyung@health.nyc.gov
• Federal Fiscal Year:
  2023
• Performing Organization:
  New York City Health/Mental Hygiene
• Peer Reviewed:
  True
• Start Date:
  20090430
• Source Full Name:
  International Journal of Environmental Research and Public Health
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7c2b2ad36fe0f0d86cc482c647b2686084c4b20fa930de47e52dd6575e98e72e38b265516bb20c45e1da644ebbc9d4b55af143305027e5bf08ae6f98203439d1
• Download URL:
  https://stacks.cdc.gov/view/cdc/231290/cdc_231290_DS1.pdf
• File Type:
  [PDF - 352.09 KB ]