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Longitudinal Determinants of Depression Among World Trade Center Health Registry Enrollees, 14–15 Years After the 9/11 Attacks



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  • Personal Author:
  • Description:
    Background: Exposure to the September 11, 2001 (9/11) terrorist attacks has been found to be associated with posttraumatic stress disorder (PTSD) and comorbid PTSD and depression up to 10-11 years post-disaster. However, little is known about the longitudinal predictors of mental health conditions over time. Methods: We examined longitudinal determinants of depression within strata of PTSD among 21,258 enrollees of the World Trade Center Health Registry who completed four questionnaires over 14 years of follow-up (Wave 1 in 2003-04; Wave 2 in 2005-06; Wave 3 in 2011-12; and Wave 4 in 2015-16). PTSD status was measured using the PTSD checklist on all four waves and defined as a score of > 44; depression was assessed using the 8-item Patient Health Questionnaire at Waves 3 and 4 and defined as a score of > 10. Results: Across Waves 3 and 4, 18.6% experienced depression, and it was more common among those who ever had PTSD (56.1%) compared with those who had not (5.6%). Across PTSD strata, predictors of depression included low income, unemployment, low social integration and support, post-9/11 traumatic life events, and chronic physical illness. These factors also decreased the likelihood of recovering from depression. Limitations: Depression symptoms were not measured at Waves 1 and 2; data was self-reported. Conclusions: These findings highlight the substantial burden of depression in a trauma-exposed population 14-15 years post-disaster, especially among those with PTSD. Similar life stressors predicted the course of depression among those with and without PTSD which may inform public health and clinical interventions. [Description provided by NIOSH]
  • Subjects:
  • Keywords:
  • ISSN:
    0165-0327
  • Document Type:
  • Funding:
  • Genre:
  • Place as Subject:
  • CIO:
  • Topic:
  • Location:
  • Pages in Document:
    483-490
  • Volume:
    229
  • NIOSHTIC Number:
    nn:20052325
  • Citation:
    J Affect Disord 2018 Mar; 229:483-490
  • Contact Point Address:
    Melanie H. Jacobson, World Trade Center Health Registry, Division of Epidemiology, New York City Department of Health and Mental Hygiene, New York, NY 10013
  • Email:
    mjacobson@health.nyc.gov
  • Federal Fiscal Year:
    2018
  • Performing Organization:
    New York City Health/Mental Hygiene
  • Peer Reviewed:
    True
  • Start Date:
    20090430
  • Source Full Name:
    Journal of Affective Disorders
  • End Date:
    20260630
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:bd7a93ff9d2d02b26c0de2cb667b0a04429184da0c56e72a15d4085bfe0993d6a72b6a492944b72a88433e1a13bccf0301fd5da9a7bfd59ec428b8017776a77f
  • Download URL:
  • File Type:
    Filetype[PDF - 245.18 KB ]
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