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Chronic Wasting Disease Agents in Nonhuman Primates
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  1. Susceptibilities of Nonhuman Primates to Chronic Wasting Disease
    Personal Author:
    Race, Brent; Meade-White, Kimberly D.; Miller, Michael W.; Barbian, Kent D.; Rubenstein, Richard; LaFauci, Giuseppe; Cervenakova, Larisa; Favara, Cynthia; Gardner, Donald; Long, Dan; Parnell, Michael; Striebel, James; Priola, Suzette A.; Ward, Anne; Williams, Elizabeth S.; Race, Richard; Chesebro, Bruce;
    Published:
    Sep 2009
    Source:
    Emerg Infect Dis. 15(9):1366-1376.
    Description:
    Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy, or prion disease, that affects deer, elk, and moose. Human susceptibility to CWD remains unproven despite likely exposure to CWD-infected cervids. We used 2 nonhuman primate ...
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    Filetype[PDF - 775.62 KB]
  2. Foodborne Transmission of Bovine Spongiform Encephalopathy to Nonhuman Primates
    Personal Author:
    Holznagel, Edgar; Yutzy, Barbara; Schulz-Schaeffer, Walter; Kruip, Carina; Hahmann, Uwe; Bierke, Pär; Torres, Juan-Maria; Kim, Yong-Sun; Thomzig, Achim; Beekes, Michael; Hunsmann, Gerhard; Loewer, Johannes;
    Published:
    May 2013
    Source:
    Emerg Infect Dis. 19(5):712-720.
    Description:
    Risk for human exposure to bovine spongiform encephalopathy (BSE)-inducing agent was estimated in a nonhuman primate model. To determine attack rates, incubation times, and molecular signatures, we orally exposed 18 macaques to 1 high dose of brain m...
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    Filetype[PDF - 2.71 MB]
  3. U.S. Public Health Service guideline on infectious disease issues in xenotransplantation
    Corporate Author:
    Center for Biologics Evaluation and Research (U.S.). Centers for Diseases Control and Prevention (U.S.). National Center for Infectious Diseases (U.S.). United States, Department of Health, Education, and Welfare., Office of the Assistant Secretary for Planning and Evaluation. United States, Health Resources and Services Administration..
    Published:
    August 24, 2001
    Series:
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 50, no. RR-15
    Description:
    Several developments have fueled the renewed interest in xenotransplantation--the use of live animal cells, tissues and organs in the treatment or mitigation of human disease. The world-wide, critical shortage of human organs available for transplant...
    Status:
    current
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  4. Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion
    Personal Author:
    Herbst, Allen; Velásquez, Camilo Duque; Triscott, Elizabeth; Aiken, Judd M.; McKenzie, Debbie;
    Published:
    Sep 2017
    Source:
    Emerg Infect Dis. 23(9):1598-1600.
    Description:
    Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95(+), into mice resulted in infection. Thus, emerge...
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  5. MMWR. Morbidity and mortality weekly report, Vol. 37, no. 45, November 18, 1988
    Corporate Author:
    Centers for Disease Control (U.S.)
    Published:
    November 18, 1988
    Series:
    MMWR. Morbidity and mortality weekly report ; v. 37, no. 45
    Description:
    State-specific estimates of smoking-attributable mortality and years of potential life lost--United States, 1985 -- Guidelines to prevent simian immunodeficiency virus infection in laboratory workers and animal handlers -- Table I. Summary-cases spec...
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    Filetype[PDF - 2.46 MB]