Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Miller, Michael W. ; Williams, Elizabeth S. ; Hobbs, N. Thompson ; Wolfe, Lisa L. ;
Miller, Michael W. ; Williams, Elizabeth S. ; Hobbs, N. Thompson ; Wolfe, Lisa L. ; Less -
Description:
Whether transmission of the chronic wasting disease (CWD) prion among cervids requires direct interaction with infected animals has been unclear. We report that CWD can be transmitted to susceptible animals indirectly, from environments contaminated by excreta or decomposed carcasses. Under experimental conditions, mule deer (Odocoileus hemionus) became infected in two of three paddocks containing naturally infected deer, in two of three paddocks where infected deer carcasses had decomposed in situ =1.8 years earlier, and in one of three paddocks where infected deer had last resided 2.2 years earlier. Indirect transmission and environmental persistence of infectious prions will complicate efforts to control CWD and perhaps other animal prion diseases.
Subject:
[+]
Animals
Cervid
Chronic Wasting Disease (CWD)
Deer
Environmental Exposure
Epidemiology
Feces
Female
Histocytochemistry
Male
Mule Deer
Odocoileus Hemionus
Palatine Tonsil
Prion
Prions
Research
Transmissible Spongiform Encephalopathy (TSE)
Wasting Disease, Chronic

Source:
Emerg Infect Dis. 10(6):1003-1006. ;
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:14ae85a73d82ad28f1ed505b58e181dc1d77fdfa6d937d74e56604cd27cb1ff5
File Type:

Supporting Files

• 	04-0010-F.gif	gif
  	04-0010-F.jpg	jpeg
  	04-0010-M1.jpg	jpeg
  	04-0010.nxml	txt
  	license.txt	txt

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