Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Miller, Michael W. ; Williams, Elizabeth S. ; Hobbs, N. Thompson ; Wolfe, Lisa L.
Miller, Michael W. ; Williams, Elizabeth S. ; Hobbs, N. Thompson ; Wolfe, Lisa L. Less -
Description:
Whether transmission of the chronic wasting disease (CWD) prion among cervids requires direct interaction with infected animals has been unclear. We report that CWD can be transmitted to susceptible animals indirectly, from environments contaminated by excreta or decomposed carcasses. Under experimental conditions, mule deer (Odocoileus hemionus) became infected in two of three paddocks containing naturally infected deer, in two of three paddocks where infected deer carcasses had decomposed in situ =1.8 years earlier, and in one of three paddocks where infected deer had last resided 2.2 years earlier. Indirect transmission and environmental persistence of infectious prions will complicate efforts to control CWD and perhaps other animal prion diseases.
Subjects:
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Animals Cervid Chronic Wasting Disease (CWD) Deer Environmental Exposure Epidemiology Feces Female Histocytochemistry Male Mule Deer Odocoileus Hemionus Palatine Tonsil Prion Prions Research Transmissible Spongiform Encephalopathy (TSE) Wasting Disease, Chronic
Source:
Emerg Infect Dis. 10(6):1003-1006.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:14ae85a73d82ad28f1ed505b58e181dc1d77fdfa6d937d74e56604cd27cb1ff5
Download URL:
https://stacks.cdc.gov/view/cdc/14580/cdc_14580_DS1.pdf
File Type:

Supporting Files

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