Using a Single Daytime Performance Test to Identify Most Individuals at High-Risk for Performance Impairment During Extended Wake

Details

• Personal Author:
  Barger LK ; Czeisler, Charles A. ; Duffy JF ; Gooley JJ ; Kristal BS ; Lockley SW ; Quackenbush J ; Rahman SA ; St. Hilaire MA ; Sullivan JP
• Description:
  We explored the predictive value of a neurobehavioral performance assessment under rested baseline conditions (evaluated at 8 hours awake following 8 hours of sleep) on neurobehavioral response to moderate sleep loss (evaluated at 20 hours awake two days later) in 151 healthy young participants (18-30 years). We defined each participant's response-to-sleep-loss phenotype based on the number of attentional failures on a 10-min visual psychomotor vigilance task taken at 20 hours awake (resilient: less than 6 attentional failures, n = 26 participants; non-resilient: 6 or more attentional failures, n = 125 participants). We observed that 97% of rested participants with 2 or more attentional failures (n = 73 of 151) and 100% of rested participants with 3 or more attentional failures (n = 57 of 151) were non-resilient after moderate sleep loss. Our approach can accurately identify a significant proportion of individuals who are at high risk for neurobehavioral performance impairment from staying up late with a single neurobehavioral performance assessment conducted during rested conditions. Additional methods are needed to predict the future performance of individuals who are not identified as high risk during baseline. [Description provided by NIOSH]
• Subjects:
  Behavior Nervous System Occupational Health Safety Sleep Sleep Initiation And Maintenance Disorders
• Keywords:
  Behavioral Testing Behavior Patterns Cognitive Function Neurological Reactions Sleep Deprivation
• ISSN:
  2045-2322
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  9
• NIOSHTIC Number:
  nn:20062840
• Citation:
  Sci Rep 2019 Nov; 9:16681
• Contact Point Address:
  Melissa A. St. Hilaire, Division of Sleep and Circadian Disorders, Brigham & Women's Hospital, 221 Longwood Avenue, Boston, MA, 02115, USA
• Email:
  msthilaire@rics.bwh.harvard.edu
• Federal Fiscal Year:
  2020
• NORA Priority Area:
  Healthcare and Social Assistance
• Performing Organization:
  Brigham and Women's Hospital, Boston, Massachusetts
• Peer Reviewed:
  True
• Start Date:
  20190901
• Source Full Name:
  Scientific Reports
• End Date:
  20230831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d8115fe67358202e7dbc4ab2339a17638aeb301b06f14a4695b46fc0a8d73788f1fdc201e59694b2fff5fe624661ef5b854bf276d858885e1c7e46e7c5796043
• Download URL:
  https://stacks.cdc.gov/view/cdc/226017/cdc_226017_DS1.pdf
• File Type:
  [PDF - 2.26 MB ]