Using a Single Daytime Performance Test to Identify Most Individuals at High-Risk for Performance Impairment During Extended Wake

Details

• Personal Author:
  Barger LK ; Czeisler, Charles A. ; Duffy JF ; Gooley JJ ; Kristal BS ; Lockley SW ; Quackenbush J ; Rahman SA ; St. Hilaire MA ; Sullivan JP
• Description:
  We explored the predictive value of a neurobehavioral performance assessment under rested baseline conditions (evaluated at 8 hours awake following 8 hours of sleep) on neurobehavioral response to moderate sleep loss (evaluated at 20 hours awake two days later) in 151 healthy young participants (18-30 years). We defined each participant's response-to-sleep-loss phenotype based on the number of attentional failures on a 10-min visual psychomotor vigilance task taken at 20 hours awake (resilient: less than 6 attentional failures, n = 26 participants; non-resilient: 6 or more attentional failures, n = 125 participants). We observed that 97% of rested participants with 2 or more attentional failures (n = 73 of 151) and 100% of rested participants with 3 or more attentional failures (n = 57 of 151) were non-resilient after moderate sleep loss. Our approach can accurately identify a significant proportion of individuals who are at high risk for neurobehavioral performance impairment from staying up late with a single neurobehavioral performance assessment conducted during rested conditions. Additional methods are needed to predict the future performance of individuals who are not identified as high risk during baseline. Description provided by NIOSH
• Subjects:
  • Behavior
  • Nervous System
  • Occupational Health
  • Safety
  • Sleep
  • Sleep Initiation and Maintenance Disorders
• Keywords:
  • Sleep deprivation
  • Sleep
  • Neurological reactions
  • Cognitive function
  • Behavioral testing
  • Behavior patterns
• ISSN:
  2045-2322
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  9
• NIOSHTIC Number:
  nn:20062840
• Citation:
  Sci Rep 2019 Nov; 9:16681
• Contact Point Address:
  Melissa A. St. Hilaire, Division of Sleep and Circadian Disorders, Brigham & Women's Hospital, 221 Longwood Avenue, Boston, MA, 02115, USA
• Email:
  msthilaire@rics.bwh.harvard.edu
• Federal Fiscal Year:
  2020
• NORA Priority Area:
  Healthcare and Social Assistance
• Performing Organization:
  Brigham and Women's Hospital, Boston, Massachusetts
• Peer Reviewed:
  True
• Start Date:
  20190901
• Source Full Name:
  Scientific Reports
• End Date:
  20230831
• Download URL:
  https://stacks.cdc.gov/view/cdc/226017/cdc_226017_DS1.pdf
• File Type:
  [PDF - 2.26 MB]
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d8115fe67358202e7dbc4ab2339a17638aeb301b06f14a4695b46fc0a8d73788f1fdc201e59694b2fff5fe624661ef5b854bf276d858885e1c7e46e7c5796043