Latency of Asbestos Disease Among Insulation Workers in the United States and Canada

Details

• Personal Author:
  Hammond EC ; Seidman H ; Selikoff IJ
• Description:
  Two thousand two hundred seventy-one deaths were recorded among 17,800 asbestos insulation workers observed from January 1, 1967-December 31, 1976. There was little increase in cancer deaths or of asbestosis in less than 15-19 years from onset of employment. In general, though, the period of clinical latency was 2-4 decades or more and there were important differences among the several asbestos-associated diseases. Lung cancer peaked at about 30-35 years from onset and asbestosis at 40-45 years. Each tended to decline in incidence afterwards. Pleural and peritoneal mesothelioma reached their highest incidence later than lung cancer, but the incidence did not decline. In studies of effects of asbestos exposure, it appears advantageous to observe for at least 35-40 years or more from onset of exposure and to analyze the experience in duration-from-onset categories. If this is not possible, only the very limited early effects will be identified and the full import of the exposure may not be appreciated. [Description provided by NIOSH]
• Subjects:
  Asbestos Inorganic Chemicals Lung Lung Diseases Mortality Neoplasms Occupational Health Respiratory System Respiratory Tract Diseases Safety
• Keywords:
  Asbestos Industry Asbestosis Asbestos Workers Cancer Insulation Workers Lung Cancer Mesothelioma Mortality Rates Respiratory Diseases
• ISSN:
  0008-543X
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  46
• Issue:
  12
• NIOSHTIC Number:
  nn:20061269
• Citation:
  Cancer 1980 Dec; 46(12):2736-2740
• Contact Point Address:
  Irving J. Selikoff MD, The Mount Sinai Medical Center, One Gustave L, Levy Place, New York, NY 10029
• CAS Registry Number:
  Asbestos (CAS RN 1332-21-4)
• Federal Fiscal Year:
  1981
• Performing Organization:
  Mount Sinai School of Medicine, New York, New York
• Peer Reviewed:
  True
• Start Date:
  19700501
• Source Full Name:
  Cancer
• End Date:
  19790630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:711317ffd35e458fbec24805409aa178ffa3e25972007d5801c51ef761250f8532db2796de9c69a6cb2572bd2220bc4dc2dad744c5d4bf23690357d278f86f39
• Download URL:
  https://stacks.cdc.gov/view/cdc/224850/cdc_224850_DS1.pdf
• File Type:
  [PDF - 374.38 KB ]