The Environment and Male Fertility: Recent Research on Emerging Chemicals and Semen Quality

Details

• Personal Author:
  Harser R
• Description:
  Scientific and public concern about the potential risk of environmental chemicals to male reproductive health has been heightened by reports of downward trends in semen quality, as well as increased rates of developmental urogenital tract anomalies and testicular cancer. Of particular concern is whether some contemporary-use environmental chemicals alter semen quality. Specific toxicants of interest include phthalates and pesticides, as well as polychlorinated biphenyls (PCBs). The human data on the relationship of semen quality with phthalate and pesticide exposure are limited and do not currently allow for a definitive conclusion on whether adult exposure, at background environmental levels, alters semen quality. However, the epidemiologic data support an inverse association of PCBs with reduced semen quality, specifically reduced sperm motility. The associations found were generally consistent across studies despite a range of PCB levels. In addition to the chemicals discussed, there are additional classes of chemicals that require further study on their relation with human semen quality. [Description provided by NIOSH]
• Subjects:
  Age Factors Environment Environmental Exposure Environmental Monitoring Epidemiology Insecticides Men Occupational Health Phthalic Acids Polychlorinated Biphenyls Safety Urogenital Diseases Urogenital System

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• Keywords:
  Age Factors Author Keywords: Environment Chemicals Environmental Exposure Environmental Monitoring Fertility Health Effects Humans PCBs Pesticides Phthalates Physiology Polychlorinated Biphenyls Reproductive Effects Reproductive Hazards Reproductive Health Reproductive System Disorders Sperm

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• ISSN:
  1526-4564
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  156-167
• Volume:
  24
• Issue:
  3
• NIOSHTIC Number:
  nn:20060396
• Citation:
  Semin Reprod Med 2006 Jul; 24(3):156-167
• Contact Point Address:
  Russ Hauser, M.D., Sc.D., M.P.H., Associate Professor of Occupational Health, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue Building I-1405, Boston, MA 02115
• Email:
  rhauser@hohp.harvard.edu
• CAS Registry Number:
  1,1′-Biphenyl, chloro derivs. (CAS RN 1336-36-3)
• Federal Fiscal Year:
  2006
• Performing Organization:
  Harvard School of Public Health
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Seminars in Reproductive Medicine
• End Date:
  20280630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:489361f4c2deb67f7c4014a66dcc4d34aaf231af30220c07d47ecc765becf026dbb5fd4ffb446b4febb166500549ab6b9afb2de17a10a9fdcf0cf4319e504853
• Download URL:
  https://stacks.cdc.gov/view/cdc/224319/cdc_224319_DS1.pdf
• File Type:
  [PDF - 132.13 KB ]