The Concentration and Chemical Status of Arsenic in the Early Placentas of Arsenate-Dosed Hamsters

Details

• Personal Author:
  Ferm VH ; Hanlon DP
• Description:
  We determined the concentration and chemical status of arsenic in the placentas of hamsters following continuous exposure via the osmotic minipump to minimally and frankly teratogenic doses of arsenate. Close to 70% of the placental arsenic is bound to macromolecules, two-thirds of which is dialyzable. The remaining 30% of arsenic consists of low molecular weight species, predominantly inorganic arsenic. This mix is the same for minimally teratogenic and frankly teratogenic doses of arsenate. [Description provided by NIOSH]
• Subjects:
  Animals Arsenic Inorganic Chemicals Occupational Health Pregnancy Safety Teratogenesis
• Keywords:
  Animal Studies Arsenates Prenatal Exposure Teratogens Toxic Effects
• ISSN:
  0013-9351
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New Hampshire ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  42
• Issue:
  2
• NIOSHTIC Number:
  nn:20060243
• Citation:
  Environ Res 1987 Apr; 42(2):546-552
• CAS Registry Number:
  Arsenic (CAS RN 7440-38-2)
• Federal Fiscal Year:
  1987
• Peer Reviewed:
  True
• Source Full Name:
  Environmental Research
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:80dc7fb0af387dcf52b509c1645e692ea95fe9609163b916a805a124ce7f1d0d894a16b6363eec9f9767016caa0b46b9e58aa834bd15156fe63ec3545f7d7063
• Download URL:
  https://stacks.cdc.gov/view/cdc/224201/cdc_224201_DS1.pdf
• File Type:
  [PDF - 427.66 KB ]