Environmental Pyrethroid and Organophosphorus Insecticide Exposures and Sperm Concentration

Details

• Personal Author:
  Barr DB ; Perry MJ ; Venners SA ; Xu X
• Description:
  Background: There is growing concern that poisoning and other adverse health effects are increasing because organophosphorous (OP) insecticides are now being used in combination with pyrethroid (PYR) insecticides to enhance the toxic effects of PYR insecticides on target insects, especially those that have developed PYR resistance. Objectives: We conducted a pilot biomonitoring study to determine whether men in our reproductive cohort study were being exposed to pesticides environmentally by virtue of frequenting an agricultural setting. Methods: We screened 18 randomly selected urine samples collected from male participants of reproductive age for 24 parent compounds and metabolites of pesticides and examined the results in relation to sperm concentration. Results: Results showed high prevalence of exposure to OP and PYR pesticides and our preliminary analyses provided some suggestion that the higher exposure group had lower sperm concentration. Conclusions: The potential of OP/PYR mixtures to have enhanced human toxicity needs more research attention. Description provided by NIOSH
• Subjects:
  • Endocrine System
  • Environmental Exposure
  • Hazardous Substances
  • Insecticides
  • Men
  • Occupational Health
  • Organophosphates
  • Risk Assessment
  • Risk Factors
  • Safety
  More +
• Keywords:
  • Environmental exposure
  • Pyrethroids
  • Organophosphorus compounds
  • Organophosphorus insecticides
  • Organophosphorus pesticides
  • Pesticides
  • Humans
  • Men
  • Exposure levels
  • Risk factors
  More +
• ISSN:
  0890-6238
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Georgia ; Illinois ; Massachusetts ; OSHA Region 1 ; OSHA Region 4 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  113-118
• Volume:
  23
• Issue:
  1
• NIOSHTIC Number:
  nn:20059184
• Citation:
  Reprod Toxicol 2007 Jan; 23(1):113-118
• Contact Point Address:
  Melissa J. Perry, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Building 1, Room 1413, Boston, MA 02115
• Email:
  mperry@hsph.harvard.edu
• Federal Fiscal Year:
  2007
• Performing Organization:
  Harvard School of Public Health
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Reproductive Toxicology
• End Date:
  20280630
• Download URL:
  https://stacks.cdc.gov/view/cdc/223479/cdc_223479_DS1.pdf
• File Type:
  [PDF - 125.45 KB]
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:3effea3effd02b9c971f2989f5c1e840cc617ab9d1d515672e7b76ab7c015163a5c764fa36015867183d780b47c964e8e2d9fe960fc0d003835f60b82530bb89