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Change in 9/11-Related Post-Traumatic Stress Symptoms Following Cancer Diagnosis



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  • Personal Author:
  • Description:
    Objective: Cancer can be a life-threatening stressor that may evoke pre-existing post-traumatic stress disorder (PTSD). We assessed change in 9/11-related PTSD symptoms following cancer diagnosis in a 9/11-exposed cohort, the World Trade Center Health Registry. Methods: We examined enrollees who had a first-time post-9/11 invasive cancer diagnosis and at least one pre- and two post-diagnosis 9/11-related PTSD assessments from enrolment through 2015. PTSD symptoms were measured using 17-item PTSD Checklist (PCL, range 17-85). Cancer was identified from New York State Cancer Registry and categorized as localized or advanced stage. We used piecewise spline linear mixed-effects models to examine rate of change in PCL scores from pre- to post-diagnosis periods, and whether the change differed by gender or stage, with time as fixed and random effects, adjusting for baseline age, race, and education. Results: 9/11-related PTSD symptoms were slightly increasing in the pre-diagnosis period, while this trend reversed in the post-diagnosis period (beta: -0.38; 95% CI: -0.60, -0.15). This trend was driven by male rescue/recovery workers (RRW), among whom significant decrease in rate of change in PCL scores was observed for those with advanced stage (slope change difference [95% CI]: -1.81 [-2.73, -0.90]). No significant difference in rate of change was observed among non-RRW. Among females, PCL scores tended to decrease slightly, with no significant difference in rate of change between pre- and post-diagnosis periods. Conclusions: We observed significant reduction in the rate of change in 9/11-related PTSD symptoms among male RRW. The underlying mechanism is unknown, necessitating future research. [Description provided by NIOSH]
  • Subjects:
  • Keywords:
  • ISSN:
    1057-9249
  • Document Type:
    Text
  • Funding:
    Cooperative Agreement
  • Genre:
    Journal Article
  • Place as Subject:
  • CIO:
    National Institute for Occupational Safety and Health (NIOSH)
  • Topic:
    Workplace Safety & Health
  • Location:
    North America
  • Volume:
    31
  • Issue:
    5
  • NIOSHTIC Number:
    nn:20064137
  • Citation:
    Psychooncology 2022 May; 31(5):717-724
  • Contact Point Address:
    Janette Yung, MPH New York City Department of Health and Mental Hygiene World Trade Center Health Registry 30-30 47th Ave, 4th floor, CN 6-W Long Island City, NY 11101
  • Email:
    jyung@health.nyc.gov
  • Federal Fiscal Year:
    2022
  • Performing Organization:
    New York City Health/Mental Hygiene
  • Peer Reviewed:
    True
  • Start Date:
    20090430
  • Source Full Name:
    Psycho-Oncology
  • End Date:
    20260630
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:ecdc59589c72e52e78c3a0b2047cb844544d4cf1874e53a347c79a2428eb11f13687cbbac439004ac10dac5aa197307f01363460413212fb1f2127db7b6178b3
  • Download URL:
  • File Type:
    Filetype[PDF - 309.64 KB ]
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