Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Page, Anne-Laure ; Jusot, Viviane ; Mamaty, Abdoul-Aziz ; Adamou, Lagare ; Kaplon, Jérôme ; Pothier, Pierre ; Djibo, Ali ; Manzo, Mahamane L. ; Toure, Brahima ; Langendorf, Céline ; Collard, Jean-Marc ; Grais, Rebecca F.
• Description:
  Knowledge of rotavirus epidemiology is necessary to make informed decisions about vaccine introduction and to evaluate vaccine impact. During April 2010-March 2012, rotavirus surveillance was conducted among 9,745 children <5 years of age in 14 hospitals/health centers in Niger, where rotavirus vaccine has not been introduced. Study participants had acute watery diarrhea and moderate to severe dehydration, and 20% of the children were enrolled in a nutrition program. Of the 9,745 children, 30.6% were rotavirus positive. Genotyping of a subset of positive samples showed a variety of genotypes during the first year, although G2P[4] predominated. G12 genotypes, including G12P[8], which has emerged as a predominant strain in western Africa, represented >80% of isolates during the second year. Hospitalization and death rates and severe dehydration among rotavirus case-patients did not differ during the 2 years. The emergence of G12P[8] warrants close attention to the characteristics of associated epidemics and possible prevention measures.
• Subjects:
  Child, Preschool Feces Genotype Hospitalization Humans Infant Infant, Newborn Rotavirus Rotavirus Infections
• Source:
  Emerg Infect Dis. 20(4):573-580.
• Document Type:
  Journal Article
• Place as Subject:
  Niger
• Location:
  Africa
• Volume:
  20
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:0b7906d067c78b8d019ec519a771926e9697d28f0342325330ede03e91495706
• Download URL:
  https://stacks.cdc.gov/view/cdc/22214/cdc_22214_DS1.pdf
• File Type:
  [PDF - 460.14 KB ]