Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health

Middleton, Deborah; Pallister, Jackie; Klein, Reuben; Feng, Yan-Ru; Haining, Jessica; Arkinstall, Rachel; Frazer, Leah; Huang, Jin-An; Edwards, Nigel; Wareing, Mark; Elhay, Martin; Hashmi, Zia; Bingham, John; Yamada, Manabu; Johnson, Dayna; White, John; Foord, Adam; Heine, Hans G.; Marsh, Glenn A.; Broder, Christopher C.; Wang, Lin-Fa

Back to Previous Page

Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health

Published Date:

Mar 2014

Source:

Emerg Infect Dis. 20(3):372-379.

[PDF-416.23 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Middleton, Deborah ; Pallister, Jackie ; Klein, Reuben ; Feng, Yan-Ru ; Haining, Jessica ; ... More ▼

Description:

In recent years, the emergence of several highly pathogenic zoonotic diseases in humans has led to a renewed emphasis on the interconnectedness of human, animal, and environmental health, otherwise known as One Health. For example, Hendra virus (HeV), a zoonotic paramyxovirus, was discovered in 1994, and since then, infections have occurred in 7 humans, each of whom had a strong epidemiologic link to similarly affected horses. As a consequence of these outbreaks, eradication of bat populations was discussed, despite their crucial environmental roles in pollination and reduction of the insect population. We describe the development and evaluation of a vaccine for horses with the potential for breaking the chain of HeV transmission from bats to horses to humans, thereby protecting horse, human, and environmental health. The HeV vaccine for horses is a key example of a One Health approach to the control of human disease.

Subject:

[+]

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Main Document Checksum:

[+]

File Type:

Supporting Files:

	13-1159-F1.gif	image/gif
	13-1159-F1.jpg	image/jpeg
	13-1159-F2.gif	image/gif
	13-1159-F2.jpg	image/jpeg
	13-1159.nxml	text/plain
	license.txt	text/plain

No Related Documents.

Experimental Infection of Horses with Hendra Virus/Australia/Horse/2008/Redlands

[PDF - 470.01 KB]

Personal Author:

Marsh, Glenn A. ; Haining, Jessica ; ...

Published Date:

Dec 2011

Source:

Emerg Infect Dis. 17(12):2232-2238.

Description:

Hendra virus (HeV) is a highly pathogenic zoonotic paramyxovirus harbored by Australian flying foxes with sporadic spillovers directly to horses. Alth...

File Type:

[PDF - 470.01 KB]

File Type:

[PDF - 470.01 KB]
Hendra Virus Outbreak with Novel Clinical Features, Australia

[PDF - 36.78 KB]

Personal Author:

Field, Hume ; Schaaf, Kylie ; ...

Published Date:

Feb 2010

Source:

Emerg Infect Dis. 16(2):338-340.

Description:

To determine the epidemiologic and clinical features of a 2008 outbreak of Hendra virus infection in a veterinary clinic in Australia, we investigated...

File Type:

[PDF - 36.78 KB]

File Type:

[PDF - 36.78 KB]
Genome Sequence Conservation of Hendra Virus Isolates during Spillover to Horses, Australia

[PDF - 406.05 KB]

Personal Author:

Marsh, Glenn A. ; Todd, Shawn ; ...

Published Date:

Nov 2010

Source:

Emerg Infect Dis. 16(11):1767-1769.

Description:

Bat-to-horse transmission of Hendra virus has occurred at least 14 times. Although clinical signs in horses have differed, genome sequencing has demon...

File Type:

[PDF - 406.05 KB]

File Type:

[PDF - 406.05 KB]
Hendra Virus Infection in Dog, Australia, 2013

[PDF - 364.79 KB]

Personal Author:

Kirkland, Peter D. ; Gabor, Melinda ; ...

Published Date:

Dec 2015

Source:

Emerg Infect Dis. 21(12):2182-2185

Description:

Hendra virus occasionally causes severe disease in horses and humans. In Australia in 2013, infection was detected in a dog that had been in contact w...

File Type:

[PDF - 364.79 KB]

File Type:

[PDF - 364.79 KB]
Human Hendra Virus Encephalitis Associated with Equine Outbreak, Australia, 2008

[PDF - 133.39 KB]

Personal Author:

Playford, Elliott G. ; McCall, Brad ; ...

Published Date:

Feb 2010

Source:

Emerg Infect Dis. 16(2):219-223.

Description:

A recent Hendra virus outbreak at a veterinary clinic in Brisbane, Queensland, Australia, involved 5 equine and 2 human infections. In contrast to pre...

File Type:

[PDF - 133.39 KB]

File Type:

[PDF - 133.39 KB]

Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health

Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health

You May Also Like:

Have Questions?

CDC INFORMATION

CONNECT WITH CDC