Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Middleton, Deborah ; Pallister, Jackie ; Klein, Reuben ; Feng, Yan-Ru ; Haining, Jessica ; ... More +
Middleton, Deborah ; Pallister, Jackie ; Klein, Reuben ; Feng, Yan-Ru ; Haining, Jessica ; Arkinstall, Rachel ; Frazer, Leah ; Huang, Jin-An ; Edwards, Nigel ; Wareing, Mark ; Elhay, Martin ; Hashmi, Zia ; Bingham, John ; Yamada, Manabu ; Johnson, Dayna ; White, John ; Foord, Adam ; Heine, Hans G. ; Marsh, Glenn A. ; Broder, Christopher C. ; Wang, Lin-Fa Less -
Description:
In recent years, the emergence of several highly pathogenic zoonotic diseases in humans has led to a renewed emphasis on the interconnectedness of human, animal, and environmental health, otherwise known as One Health. For example, Hendra virus (HeV), a zoonotic paramyxovirus, was discovered in 1994, and since then, infections have occurred in 7 humans, each of whom had a strong epidemiologic link to similarly affected horses. As a consequence of these outbreaks, eradication of bat populations was discussed, despite their crucial environmental roles in pollination and reduction of the insect population. We describe the development and evaluation of a vaccine for horses with the potential for breaking the chain of HeV transmission from bats to horses to humans, thereby protecting horse, human, and environmental health. The HeV vaccine for horses is a key example of a One Health approach to the control of human disease.
Subject:
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Antibodies, Viral
Environmental Health
Female
Ferrets
Guinea Pigs
Hendra Virus
Henipavirus Infections
Horse Diseases
Horses
Humans
Immunization
Neutralization Tests
One Health
Viral Vaccines
Zoonoses

Source:
Emerg Infect Dis. 20(3):372-379.
Document Type:
Journal Article
Place as Subject:
Australia
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:31f93d98becce4d600bce7cf906d71e2638a8c2175b903a2a664fd60d6b5475c
File Type:

Supporting Files

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