Biological Monitoring of Wood-Smoke Exposure

Details

• Personal Author:
  Naeher LP ; Simpson CD
• Description:
  It has been clearly established that exposure to wood smoke is associated with a variety of adverse health effects in humans. However, we still have much to learn about the relationship between wood-smoke exposure and disease, including determination of what should be considered a "safe" level of exposure, and whether wood smoke should be regulated separately from other sources of air pollution. To help answer these questions, improved measures of exposure in populations exposed to wood smoke are required. In this mini-review we discuss how biomarkers of exposure can be used to complement the current suite of methods used to assess wood-smoke exposures. We critically review the compounds that are currently being evaluated as biomarkers of exposure to wood smoke, and we identify the strengths and weaknesses of these compounds. We find that, in general, these compounds show promise in situations where wood-smoke exposures are high, but where exposures are low non-wood-smoke sources are likely to be the major determinants of biomarker levels. We also outline a research framework that will move this field forward and maximize the potential for wood-smoke biomarkers to add value to epidemiological studies of wood-smoke health effects. [Description provided by NIOSH]
• Subjects:
  Air Pollution Biomarkers Epidemiology Occupational Health Safety Wood
• Keywords:
  Air Pollution Author Keywords: Biological Monitoring Exposure Assessment Exposure Limits Health Effects Smoke Inhalation Wood Smoke
• ISSN:
  0895-8378
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Georgia ; OSHA Region 10 ; OSHA Region 4 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  99-103
• Volume:
  22
• Issue:
  2
• NIOSHTIC Number:
  nn:20054746
• Citation:
  Inhal Toxicol 2010 Feb; 22(2):99-103
• Contact Point Address:
  Christopher D. Simpson, The University of Washington, School of Public Health, Department of Environmental and Occupational Health Sciences, Seattle, WA 98195-7234, USA
• Email:
  simpson1@u.washington.edu
• Federal Fiscal Year:
  2010
• Performing Organization:
  University of Washington
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Inhalation Toxicology
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7636433ea68e7e058403d78b5056f36f3ade1f13ccc5b055525af7bc5fdb74e3ca3f387f3032a17d108e1b7c44cabe10f3114538031d5ca86d4fac84b9b5673b
• Download URL:
  https://stacks.cdc.gov/view/cdc/217182/cdc_217182_DS1.pdf
• File Type:
  [PDF - 715.84 KB ]