Biomonitoring Human Exposure to Household Air Pollution and Association with Self-Reported Health Symptoms – a Stove Intervention Study in Peru

Details

• Personal Author:
  Commodore A ; Gil AI ; Hartinger S ; Hubbard K ; Lanata CF ; Lewin M ; Li Z ; Mäusezahl D ; Naeher LP ; Pittman E ; Sjödin, Andreas ; Trinidad D
• Description:
  Background: Household air pollution (HAP) from indoor biomass stoves contains harmful pollutants, such as polycyclic aromatic hydrocarbons (PAHs), and is a leading risk factor for global disease burden. We used biomonitoring to assess HAP exposure and association with self-reported symptoms in 334 non-smoking Peruvian women to evaluate the efficacy of a stove intervention program. Methods: We conducted a cross-sectional study within the framework of a community randomized control trial. Using urinary PAH metabolites (OH-PAHs) as the exposure biomarkers, we investigated whether the intervention group (n = 155, with new chimney-equipped stoves) were less exposed to HAP compared to the control group (n = 179, with mostly open-fire stoves). We also estimated associations between the exposure biomarkers, risk factors, and self-reported health symptoms, such as recent eye conditions, respiratory conditions, and headache. Results: We observed reduced headache and ocular symptoms in the intervention group than the control group. Urinary 2-naphthol, a suggested biomarker for inhalation PAH exposure, was significantly lower in the intervention group (GM with 95% CI: 13.4 [12.3, 14.6] ug/g creatinine) compared to control group (16.5 [15.0, 18.0] ug/g creatinine). Stove type and/or 2-naphthol was associated with a number of self-reported symptoms, such as red eye (adjusted OR with 95% CI: 3.80 [1.32, 10.9]) in the past 48 h. Conclusions: Even with the improved stoves, the biomarker concentrations in this study far exceeded those of the general populations and were higher than a no-observed-genotoxic-effect-level, indicating high exposure and a potential for increased cancer risk in the population. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Air Pollution, Indoor Biomarkers Energy Metabolism Hydrocarbons Occupational Health Polycyclic Aromatic Hydrocarbons Safety Urine Wood
• Keywords:
  Air Pollutants Author Keywords: 1-hydroxypyrene Biomonitoring Cooking Equipment Cross Sectional Studies Household Air Pollution Indoor Air Pollution Metabolites Polycyclic Aromatic Hydrocarbon Polycyclic Aromatic Hydrocarbons Smoke Inhalation Stove Intervention Urinalysis Woodsmoke

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• ISSN:
  0160-4120
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Alabama ; Georgia ; OSHA Region 4 ; South Carolina
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  195-203
• Volume:
  97
• NIOSHTIC Number:
  nn:20050697
• Citation:
  Environ Int 2016 Dec; 97:195-203
• Contact Point Address:
  Zheng Li, PhD, MPH, MS, 4770 Buford Highway, F-57, Atlanta, GA 30341
• Email:
  ZJLi@cdc.gov
• Federal Fiscal Year:
  2017
• Performing Organization:
  University of Alabama at Birmingham
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Environmental International
• End Date:
  20270630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:66eaa4e992db0866d32a24769962dc0b51d7f42c9c269d0dfcd54c1e15d21f05ca95bda298d4f6c8b77b1c1022b817695f1fe07d75092bab08124c649ee2462d
• Download URL:
  https://stacks.cdc.gov/view/cdc/210940/cdc_210940_DS1.pdf
• File Type:
  [PDF - 601.97 KB ]