A 3D-Printed, Portable, Optical-Sensing Platform for Smartphones Capable of Detecting the Herbicide 2,4-Dichlorophenoxyacetic Acid

Details

• Personal Author:
  Du D ; Li L ; Lin Y ; Smith JN ; Sun R ; Timchalk C ; Wang S ; Wang Y ; Yang M ; Zeinhom MMA
• Description:
  Onsite rapid detection of herbicides and herbicide residuals in environmental and biological specimens are important for agriculture, environmental concerns, food safety, and health care. The traditional method for herbicide detection requires expensive laboratory equipment and a long turnaround time. In this work, we developed a single-stripe microliter plate smartphone-based colorimetric device for rapid and low-cost in-field tests. This portable smartphone platform is capable of screening eight samples in a single-stripe microplate. The device combined the advantages of small size (50 × 100 × 160 mm3) and low cost ($10). The platform was calibrated by using two different dye solutions, i.e. methyl blue (MB) and rhodamine B, for the red and green channels. The results showed good correlation with results attained from a traditional laboratory reader. We demonstrated the application of this platform for detection of the herbicide 2,4-dichlorophenoxyacetic acid in the range of 1 to 80 ppb. Spiked samples of tap water, rat serum, plasma, and human serum were tested by our device. Recoveries obtained varied from 95.6% to 105.2% for all of the spiked samples using the microplate reader and from 93.7% to 106.9% for all of the samples using the smartphone device. This work validated that the smartphone optical-sensing platform is comparable to the commercial microplate reader; it is eligible for onsite, rapid, and low-cost detection of herbicides for environmental evaluation and biological monitoring. [Description provided by NIOSH]
• Subjects:
  Environmental Monitoring Herbicides Occupational Health Safety Software
• Keywords:
  Biological Monitoring Cell Phones Computer Applications Detectors Environmental Monitoring Sensors
• ISSN:
  0003-2700
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  89
• Issue:
  17
• NIOSHTIC Number:
  nn:20054531
• Citation:
  Anal Chem 2017 Sep; 89(17):9339-9346
• Contact Point Address:
  Dan Du, School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States
• Email:
  annie.du@wsu.edu
• CAS Registry Number:
  (2,4-Dichlorophenoxy)acetic acid (CAS RN 94-75-7)
• Federal Fiscal Year:
  2017
• NORA Priority Area:
  Agriculture, Forestry and Fishing
• Performing Organization:
  Battelle Pacific Northwest Laboratories, Richland, Washington
• Peer Reviewed:
  True
• Start Date:
  20160901
• Source Full Name:
  Analytical Chemistry
• End Date:
  20200831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0ef34b7d9dd52e87e664bc1ea2f8516ffdea8a2deba2d1a58e92322893e6c5483d447a4f9e4fbafd938f021eb3fb3a0eea0a9ab4d9eba39ac49726d72c9f5de7
• Download URL:
  https://stacks.cdc.gov/view/cdc/217062/cdc_217062_DS1.pdf
• File Type:
  [PDF - 3.18 MB ]