Meeting Report: Measuring Endocrine-Sensitive Endpoints Within the First Years of Life

Details

• Personal Author:
  Arbuckle TE ; Bornehag C-G ; Hauser R ; Jarrell J ; Legrand M ; Longnecker MP ; Main KM ; Mao CS ; Matthews S ; Mendola P ; Mieusset R ; Rovet J ; Swan SH ; Till C ; Van Vliet G ; Wade M ; Whyatt RM
• Description:
  An international workshop titled "Assessing Endocrine-Related Endpoints within the First Years of Life" was held 30 April-1 May 2007, in Ottawa, Ontario, Canada. Representatives from a number of pregnancy cohort studies in North America and Europe presented options for measuring various endocrine-sensitive endpoints in early life and discussed issues related to performing and using those measures. The workshop focused on measuring reproductive tract developmental endpoints [e.g., anogenital distance (AGD)], endocrine status, and infant anthropometry. To the extent possible, workshop participants strove to develop or recommend standardized measurements that would allow comparisons and pooling of data across studies. The recommended outcomes include thigh fat fold, breast size, vaginal cytology, AGD, location of the testis, testicular size, and growth of the penis, with most of the discussion focusing on the genital exam. Although a number of outcome measures recommended during the genital exam have been associated with exposure to endocrine-disrupting chemicals, little is known about how predictive these effects are of later reproductive health or other chronic health conditions. [Description provided by NIOSH]
• Subjects:
  Chemistry Cytology Endocrine System Occupational Health Pregnancy Safety Urogenital System Women
• Keywords:
  Anthropometry Author Keywords: Anogenital Distance Chemical Composition Chemical Properties Endocrine Disruptors Endocrine Function Endocrine System Endocrine System Disorders Genital Exam Health Effects Hormones Humans Infants Measurement Neurodevelopment Reproduction Reproductive System Reproductive Tract Development Sexual Dimorphism Testes

  More +
• ISSN:
  0091-6765
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Massachusetts ; New York ; North Carolina ; OSHA Region 1 ; OSHA Region 2 ; OSHA Region 4 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  116
• Issue:
  7
• NIOSHTIC Number:
  nn:20054350
• Citation:
  Environ Health Perspect 2008 Jul; 116(7):948-951
• Contact Point Address:
  T.E. Arbuckle, Biostatistics and Epidemiology Division, Healthy Environments and Consumer Safety Branch, Health Canada, 50 Columbine Dr., A.L. 0801A, Tunney's Pasture, Ottawa, ON K1A 0K9 Canada
• Email:
  arbuckle@hc-sc.gc.ca
• Federal Fiscal Year:
  2008
• Performing Organization:
  Harvard School of Public Health
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Environmental Health Perspectives
• End Date:
  20280630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f8e15a3df7a37a9ff88dd8ba0d5c6b4402d7c77edac81a0b38a0850b01ab0687275d9677536a966636437a574658a71d9bc028b0a78e3ce1cfda68c4bf40d0e7
• Download URL:
  https://stacks.cdc.gov/view/cdc/216935/cdc_216935_DS1.pdf
• File Type:
  [PDF - 125.38 KB ]