Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection

Hingley-Wilson, Suzanne M.; Casey, Rosalyn; Connell, David; Bremang, Samuel; Evans, Jason T.; Hawkey, Peter M.; Smith, Grace E.; Jepson, Annette; Philip, Stuart; Kon, Onn Min; Lalvani, Ajit

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection

Published Date:

Jul 2013

Source:

Emerg Infect Dis. 19(7):1138-1141.

[PDF-410.62 KB]

Details:

Personal Authors:

Hingley-Wilson, Suzanne M. ; Casey, Rosalyn ; Connell, David ; Bremang, Samuel ; Evans, Jason T. ; ... More ▼

Keywords:

[+]

Description:

Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mixed infection. Diagnostic techniques that identify mixed tubercle bacilli populations are needed to curb the spread of multidrug resistance.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Main Document Checksum:

[+]

Supporting Files:

	13-0313-F1.gif	image/gif
	13-0313-F1.jpg	image/jpeg
	13-0313-F2.gif	image/gif
	13-0313-F2.jpg	image/jpeg
	13-0313.nxml	text/plain
	license.txt	text/plain

No Related Documents.

You May Also Like:

Co-infection with Drug-Susceptible and Reactivated Latent Multidrug-Resistant Mycobacterium tuberculosis

Personal Author:

Pérez-Lago, Laura; Lirola, Miguel Martínez; Navarro, Yurena; Herranz, Marta; Ruiz-Serrano, María Jesús; Bouza, Emilio; García-de-Viedma, Darío;

Published:

Nov 2015

Source:

Emerg Infect Dis. 21(11):2098-2100

File Type:

[PDF - 848.73 KB]
Sensitivity to Polymyxin B in El Tor Vibrio cholerae O1 Strain, Kolkata, India

Personal Author:

Samanta, Prosenjit; Ghosh, Priyanka; Chowdhury, Goutam; Ramamurthy, Thandavarayan; Mukhopadhyay, Asish K.;

Published:

Nov 2015

Source:

Emerg Infect Dis. 21(11):2100-2102

File Type:

[PDF - 566.87 KB]
Epidemiologic Shift in Candidemia Driven by Candida auris, South Africa, 2016–20171

Personal Author:

van Schalkwyk, Erika; Mpembe, Ruth S.; Thomas, Juno; Shuping, Liliwe; Ismail, Husna; Lowman, Warren; Karstaedt, Alan S.; Chibabhai, Vindana; Wadula, Jeannette; Avenant, Theunis; Messina, Angeliki; Govind, Chetna N.; Moodley, Krishnee; Dawood, Halima; Ramjathan, Praksha; Govender, Nelesh P.;

Corporate Author:

for GERMS-SA

Published:

September 2019

Source:

Emerg Infect Dis. 25(9):1698-1707

Description:

Candida auris is an invasive healthcare-associated fungal pathogen. Cases of candidemia, defined as illness in patients with Candida cultured from blood, were detected through national laboratory-based surveillance in South Africa during 2016-2017. W...

File Type:

[PDF - 2.00 MB]
Molecular Confirmation of Rocky Mountain Spotted Fever Epidemic Agent in Mexicali, Mexico

Personal Author:

Tinoco-Gracia, Luis; Lomelí, Moisés Rodríguez; Hori-Oshima, Sawako; Stephenson, Nicole; Foley, Janet;

Published:

Sep 2018

Source:

Emerg Infect Dis. 24(9):1723-1725.

Description:

Since 2008, a large epidemic of Rocky Mountain spotted fever has been emerging among humans and dogs in Mexicali, adjacent to the United States in Baja California, Mexico. We molecularly confirmed the causative agent; this information can be used to ...

File Type:

[PDF - 613.31 KB]
Rifampin- and Multidrug-Resistant Tuberculosis in Russian Civilians and Prison Inmates: Dominance of the Beijing Strain Family

Personal Author:

Drobniewski, Francis; Balabanova, Yanina; Ruddy, Michael; Weldon, Laura; Jeltkova, Katya; Brown, Timothy; Malomanova, Nadezdna; Elizarova, Elvira; Melentyey, Alexander; Mutovkin, Ebgeny; Zhakharova, Svetlana; Fedorin, Ivan;

Published:

Nov 2002

Source:

Emerg Infect Dis. 8(11):1320-1326.

Description:

Consecutive patient cultures (140) of Mycobacteriium tuberculosis were collected from five Russian civilian and prison tuberculosis laboratories and analyzed for rifampin (rpoB) and isoniazid resistance (inhA, katG, ahpC); transmission of Beijing fam...

File Type:

[PDF - 691.16 KB]