Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection

Hingley-Wilson, Suzanne M.; Casey, Rosalyn; Connell, David; Bremang, Samuel; Evans, Jason T.; Hawkey, Peter M.; Smith, Grace E.; Jepson, Annette; Philip, Stuart; Kon, Onn Min; Lalvani, Ajit

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection

Published Date:

Jul 2013

Source:

Emerg Infect Dis. 19(7):1138-1141.

[PDF-410.62 KB]

Details:

Personal Authors:

Hingley-Wilson, Suzanne M. ; Casey, Rosalyn ; Connell, David ; Bremang, Samuel ; Evans, Jason T. ; ... More ▼

Keywords:

[+]

Description:

Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mixed infection. Diagnostic techniques that identify mixed tubercle bacilli populations are needed to curb the spread of multidrug resistance.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

	13-0313-F1.gif	image/gif
	13-0313-F1.jpg	image/jpeg
	13-0313-F2.gif	image/gif
	13-0313-F2.jpg	image/jpeg
	13-0313.nxml	text/plain
	license.txt	text/plain

No Related Documents.

You May Also Like:

Co-infection with Drug-Susceptible and Reactivated Latent Multidrug-Resistant Mycobacterium tuberculosis

Personal Author:

Pérez-Lago, Laura; Lirola, Miguel Martínez; Navarro, Yurena; Herranz, Marta; Ruiz-Serrano, María Jesús; Bouza, Emilio; García-de-Viedma, Darío;

Published:

Nov 2015

Source:

Emerg Infect Dis. 21(11):2098-2100

File Type:

[PDF - 848.73 KB]
Sensitivity to Polymyxin B in El Tor Vibrio cholerae O1 Strain, Kolkata, India

Personal Author:

Samanta, Prosenjit; Ghosh, Priyanka; Chowdhury, Goutam; Ramamurthy, Thandavarayan; Mukhopadhyay, Asish K.;

Published:

Nov 2015

Source:

Emerg Infect Dis. 21(11):2100-2102

File Type:

[PDF - 566.87 KB]
Molecular Confirmation of Rocky Mountain Spotted Fever Epidemic Agent in Mexicali, Mexico

Personal Author:

Tinoco-Gracia, Luis; Lomelí, Moisés Rodríguez; Hori-Oshima, Sawako; Stephenson, Nicole; Foley, Janet;

Published:

Sep 2018

Source:

Emerg Infect Dis. 24(9):1723-1725.

Description:

Since 2008, a large epidemic of Rocky Mountain spotted fever has been emerging among humans and dogs in Mexicali, adjacent to the United States in Baja California, Mexico. We molecularly confirmed the causative agent; this information can be used to ...

File Type:

[PDF - 613.31 KB]
Rifampin- and Multidrug-Resistant Tuberculosis in Russian Civilians and Prison Inmates: Dominance of the Beijing Strain Family

Personal Author:

Drobniewski, Francis; Balabanova, Yanina; Ruddy, Michael; Weldon, Laura; Jeltkova, Katya; Brown, Timothy; Malomanova, Nadezdna; Elizarova, Elvira; Melentyey, Alexander; Mutovkin, Ebgeny; Zhakharova, Svetlana; Fedorin, Ivan;

Published:

Nov 2002

Source:

Emerg Infect Dis. 8(11):1320-1326.

Description:

Consecutive patient cultures (140) of Mycobacteriium tuberculosis were collected from five Russian civilian and prison tuberculosis laboratories and analyzed for rifampin (rpoB) and isoniazid resistance (inhA, katG, ahpC); transmission of Beijing fam...

File Type:

[PDF - 691.16 KB]
Effects of Mefloquine Use on Plasmodium vivax Multidrug Resistance

Personal Author:

Khim, Nimol; Andrianaranjaka, Voahangy; Popovici, Jean; Kim, Saorin; Ratsimbasoa, Arsene; Benedet, Christophe; Barnadas, Celine; Durand, Remy; Thellier, Marc; Legrand, Eric; Musset, Lise; Menegon, Michela; Severini, Carlo; Nour, Bakri Y.M.; Tichit, Magali; Bouchier, Christiane; Mercereau-Puijalon, Odile; Ménard, Didier;

Published:

Oct 2014

Source:

Emerg Infect Dis. 20(10):1637-1644.

Description:

Andes hantavirus (ANDV) causes hantavirus cardiopulmonary syndrome in Chile and is the only hantavirus for which person-to-person transmission has been proven. We describe an outbreak of 5 human cases of ANDV infection in which symptoms developed in ...

File Type:

[PDF - 546.21 KB]