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Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection
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Jul 2013
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Source: Emerg Infect Dis. 19(7):1138-1141.
[PDF-410.62 KB]
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Alternative Title:Emerg Infect Dis
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Description:Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mixed infection. Diagnostic techniques that identify mixed tubercle bacilli populations are needed to curb the spread of multidrug resistance.
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Volume:19
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Issue:7
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