Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection

Hingley-Wilson, Suzanne M.; Casey, Rosalyn; Connell, David; Bremang, Samuel; Evans, Jason T.; Hawkey, Peter M.; Smith, Grace E.; Jepson, Annette; Philip, Stuart; Kon, Onn Min; Lalvani, Ajit

Back to Previous Page

Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection

Published Date:

Jul 2013

Source:

Emerg Infect Dis. 19(7):1138-1141.

[PDF-410.62 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Hingley-Wilson, Suzanne M. ; Casey, Rosalyn ; Connell, David ; Bremang, Samuel ; Evans, Jason T. ; ... More ▼

Description:

Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mixed infection. Diagnostic techniques that identify mixed tubercle bacilli populations are needed to curb the spread of multidrug resistance.

Subject:

[+]

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Main Document Checksum:

[+]

File Type:

Supporting Files:

	13-0313-F1.gif	image/gif
	13-0313-F1.jpg	image/jpeg
	13-0313-F2.gif	image/gif
	13-0313-F2.jpg	image/jpeg
	13-0313.nxml	text/plain
	license.txt	text/plain

No Related Documents.

MDR TB Transmission, Singapore

[PDF - 300.29 KB]

Personal Author:

Chee, Cynthia B.E. ; Hsu, Li-Yang ; ...

Published Date:

Jul 2013

Source:

Emerg Infect Dis. 19(7):1151-1152.

File Type:

[PDF - 300.29 KB]

File Type:

[PDF - 300.29 KB]
Multidrug-resistant Mycobacterium tuberculosis in HIV-Infected Persons, Peru

[PDF - 269.25 KB]

Personal Author:

Campos, Pablo E. ; Suarez, Pedro G. ; ...

Published Date:

Dec 2003

Source:

Emerg Infect Dis. 9(12):1571-1578.

Description:

During 1999 to 2000, we identified HIV-infected persons with new episodes of tuberculosis (TB) at 10 hospitals in Lima, Peru, and a random sample of o...

File Type:

[PDF - 269.25 KB]

File Type:

[PDF - 269.25 KB]
Multiple Introductions of Multidrug-Resistant Tuberculosis into Households, Lima, Peru

[PDF - 189.16 KB]

Personal Author:

Cohen, Ted ; Murray, Megan ; ...

Published Date:

Jun 2011

Source:

Emerg Infect Dis. 17(6):969-975.

Description:

Two cases of multidrug-resistant tuberculosis (MDR TB) in a household are assumed to reflect within-household transmission. However, in high-incidence...

File Type:

[PDF - 189.16 KB]

File Type:

[PDF - 189.16 KB]
Mycobacterium tuberculosis Beijing Type Mutation Frequency

[PDF - 539.81 KB]

Personal Author:

de Steenwinkel, Jurriaan E.M. ; van Soolingen, Dick ; ...

Published Date:

Mar 2013

Source:

Emerg Infect Dis. 19(3):522-523.

File Type:

[PDF - 539.81 KB]

File Type:

[PDF - 539.81 KB]
Epidemiology of Primary Multidrug-Resistant Tuberculosis, Vladimir Region, Russia

[PDF - 1.85 MB]

Personal Author:

Ershova, Julia V. ; Volchenkov, Grigory V. ; ...

Published Date:

Nov 2015

Source:

Emerg Infect Dis. 21(11):2048-2051

Description:

We studied the epidemiology of drug-resistant tuberculosis (TB) in Vladimir Region, Russia, in 2012. Most cases of multidrug-resistant TB (MDR TB) wer...

File Type:

[PDF - 1.85 MB]

File Type:

[PDF - 1.85 MB]

Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection

Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection

You May Also Like:

Have Questions?

CDC INFORMATION

CONNECT WITH CDC