Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Hingley-Wilson, Suzanne M. ; Casey, Rosalyn ; Connell, David ; Bremang, Samuel ; Evans, Jason T. ; ... More +
Hingley-Wilson, Suzanne M. ; Casey, Rosalyn ; Connell, David ; Bremang, Samuel ; Evans, Jason T. ; Hawkey, Peter M. ; Smith, Grace E. ; Jepson, Annette ; Philip, Stuart ; Kon, Onn Min ; Lalvani, Ajit Less -
Description:
Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mixed infection. Diagnostic techniques that identify mixed tubercle bacilli populations are needed to curb the spread of multidrug resistance.
Subjects:
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Aged Antimicrobial Resistance Antitubercular Agents Bacteria Co-infection Coinfection Culture Techniques Delayed Diagnosis Dispatch Drug Resistance, Multiple, Bacterial Drug Sensitive Drug Therapy, Combination Ethambutol Humans Isoniazid Male Minisatellite Repeats Molecular Diagnostic Techniques Multidrug Resistant Multilocus Sequence Typing Mycobacterium Tuberculosis TB Treatment Outcome Treatment Resistance Tuberculosis, Multidrug-Resistant Tuberculosis, Pulmonary Tuberculosis And Other Mycobacteria
Source:
Emerg Infect Dis. 19(7):1138-1141.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:feb6d102514fb6fd8828bdd0ede3052f634f795d621222c6d9fc9ec6f0d96982
Download URL:
https://stacks.cdc.gov/view/cdc/21630/cdc_21630_DS1.pdf
File Type:

Supporting Files

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