Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Hingley-Wilson, Suzanne M. ; Casey, Rosalyn ; Connell, David ; Bremang, Samuel ; Evans, Jason T. ; ... More +
Hingley-Wilson, Suzanne M. ; Casey, Rosalyn ; Connell, David ; Bremang, Samuel ; Evans, Jason T. ; Hawkey, Peter M. ; Smith, Grace E. ; Jepson, Annette ; Philip, Stuart ; Kon, Onn Min ; Lalvani, Ajit Less -
Description:
Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mixed infection. Diagnostic techniques that identify mixed tubercle bacilli populations are needed to curb the spread of multidrug resistance.
Subject:
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Aged
Antimicrobial Resistance
Antitubercular Agents
Bacteria
Co-infection
Coinfection
Culture Techniques
Delayed Diagnosis
Dispatch
Drug Resistance, Multiple, Bacterial
Drug Sensitive
Drug Therapy, Combination
Ethambutol
Humans
Isoniazid
Male
Minisatellite Repeats
Molecular Diagnostic Techniques
Multidrug Resistant
Multilocus Sequence Typing
Mycobacterium Tuberculosis
TB
Treatment Outcome
Treatment Resistance
Tuberculosis, Multidrug-Resistant
Tuberculosis, Pulmonary
Tuberculosis And Other Mycobacteria

Source:
Emerg Infect Dis. 19(7):1138-1141.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:feb6d102514fb6fd8828bdd0ede3052f634f795d621222c6d9fc9ec6f0d96982
File Type:

Supporting Files

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