Community Exposure to Perfluorooctanoate: Relationships Between Serum Concentrations and Exposure Sources

Details

• Personal Author:
  Desai C ; Emmett, Edward A. ; Freeman D ; Shaw LM ; Shofer FS ; Zhang H
• Description:
  Objective: The objective of this study was to determine serum (perfluorooctanoate [PFOA]) in residents near a fluoropolymer production facility: the contributions from air, water, and occupational exposures, personal and dietary habits, and relationships to age and gender. Methods: The authors conducted questionnaire and serum PFOA measurements in a stratified random sample and volunteers residing in locations with the same residential water supply but with higher and lower potential air PFOA exposure. Results: Serum (PFOA) greatly exceeded general population medians. Occupational exposure from production processes using PFOA and residential water had additive effects; no other occupations contributed. Serum (PFOA) depended on the source of residential drinking water, and not potential air exposure. For public water users, the best-fit model included age, tap water drinks per day, servings of home-grown fruit and vegetables, and carbon filter use. Conclusions: Residential water source was the primary determinant of serum (PFOA). [Description provided by NIOSH]
• Subjects:
  Environmental Exposure Environmental Pollution Fluorocarbons Occupational Health Safety
• Keywords:
  Biological Effects Drinking Water Environmental Contamination Environmental Exposure Exposure Assessment Ground Water Water Supply
• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  48
• Issue:
  8
• NIOSHTIC Number:
  nn:20053500
• Citation:
  J Occup Environ Med 2006 Aug; 48(8):759-770
• Contact Point Address:
  Edward A. Emmett, MD, Occupational Medicine, Silverstein Pavilion, Ground Floor, 3400 Spruce St., Philadelphia, PA 19104-4284
• Email:
  emmetted@mail.med.upenn.edu
• CAS Registry Number:
  Perfluorooctanoic acid (CAS RN 335-67-1)
• Federal Fiscal Year:
  2006
• Performing Organization:
  University of Pennsylvania, Philadelphia
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  20290630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b24e02de8ebe2552c90ba775e72b8ad14abb3b7c221d2ee01f153271079641355d70a3d1433172c3a17460f24bb70c592890527aa29200cbb71f712afb7f79d6
• Download URL:
  https://stacks.cdc.gov/view/cdc/216240/cdc_216240_DS1.pdf
• File Type:
  [PDF - 562.00 KB ]