Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Douet, Jean Yves ; Zafar, Saima ; Perret-Liaudet, Armand ; Lacroux, Caroline ; Lugan, Séverine ; Aron, Naima ; Cassard, Herve ; Ponto, Claudia ; Corbière, Fabien ; Torres, Juan Maria ; Zerr, Inga ; Andreoletti, Olivier
• Description:
  We report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease. The measured infectivity levels were comparable to those reported in various animals with transmissible spongiform encephalopathies.
• Subjects:
  Blood CJD Creutzfeldt-Jakob Disease Dispatch Infectivity Prions SCJD Transmissible Spongiform Encephalopathy TSE VCJD
• Source:
  Emerg Infect Dis. 20(1):114-117.
• Document Type:
  Journal Article
• Volume:
  20
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:de47fe29bb812307b44f5dc563a422b4341d986e89d574026a241d55606a928a
• Download URL:
  https://stacks.cdc.gov/view/cdc/21517/cdc_21517_DS1.pdf
• File Type:
  [PDF - 377.67 KB ]