Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Freiesleben de Blasio, Birgitte ; Flem, Elmira ; Latipov, Renat ; Kuatbaeva, Ajnagul ; Kristiansen, Ivar Sønbø ;
Freiesleben de Blasio, Birgitte ; Flem, Elmira ; Latipov, Renat ; Kuatbaeva, Ajnagul ; Kristiansen, Ivar Sønbø ; Less -
Description:
The government of Kazakhstan, a middle-income country in Central Asia, is considering the introduction of rotavirus vaccination into its national immunization program. We performed a cost-effectiveness analysis of rotavirus vaccination spanning 20 years by using a synthesis of dynamic transmission models accounting for herd protection. We found that a vaccination program with 90% coverage would prevent ≈880 rotavirus deaths and save an average of 54,784 life-years for children <5 years of age. Indirect protection accounted for 40% and 60% reduction in severe and mild rotavirus gastroenteritis, respectively. Cost per life year gained was US $18,044 from a societal perspective and US $23,892 from a health care perspective. Comparing the 2 key parameters of cost-effectiveness, mortality rates and vaccine cost at More ▼ -->
Subject:
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Break-even Price
Cost-effectiveness
Dynamic Modeling
Herd Immunity
Kazakhstan
Research
Rotavirus
Vaccination
Vaccine
Viruses

Source:
Emerg Infect Dis. 20(1):29-37.
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:2847ab34bfe6d2d7191c082800a69133fcd08c8d653cbe07c67bb3e58e7e2d43
File Type:

Supporting Files

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  	13-0019-Techapp-s1.pdf	pdf
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