Antimony: An Unlikely Confounder in the Relationship Between Well Water Arsenic and Health Outcomes in Bangladesh

Details

• Personal Author:
  Christiani, David C. ; Kile ML ; Mahiuddin G ; McCarty KM ; Quamruzzaman Q ; Rahman M ; Senn DB
• Description:
  Recent in vitro studies have suggested a potential role for antimony as a confounder in human health studies related to arsenic in drinking water. We measured tube-well water concentrations of antimony and arsenic in the Pabna region of Bangladesh, where arsenic concentrations are known to be elevated and the concentrations of antimony have not yet been thoroughly documented. Two hundred forty-five tube-well water samples were collected from various regions in Pabna, Bangladesh, as part of an ongoing case-control study. Water samples were analyzed for arsenic and antimony concentrations by inductively coupled plasma-mass spectrometry using U.S. Environmental Protection Agency method 200.8. The arsenic concentrations in the tube-well water samples ranged from < 1 microg/L to 747 microg/L. All 245 water samples had antimony concentrations < 1 microg/L. Based on consideration of the concentrations used the in vitro studies compared with field-observed concentrations, our results do not support the hypothesis that antimony would be a significant confounder in observed relationships between arsenic exposure through drinking water and potential health outcomes in Pabna, Bangladesh. [Description provided by NIOSH]
• Subjects:
  Arsenic Diet Environmental Exposure Environmental Monitoring Epidemiology Inorganic Chemicals Men Occupational Health Poisoning Public Health Risk Assessment Risk Factors Safety Women

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• Keywords:
  Author Keywords: Antimony Bangladesh Case Control Studies Chemicals Drinking Water Environmental Monitoring Exposure Levels Humans In Vitro Studies In Vitro Study In Vivo Studies In Vivo Study Poisons Public Health Risk Assessment Risk Factors Sampling Tube Well

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• ISSN:
  0091-6765
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  112
• Issue:
  8
• NIOSHTIC Number:
  nn:20057659
• Citation:
  Environ Health Perspect 2004 Jun; 112(8):809-811
• Contact Point Address:
  D.C. Christiani, Department of Environmental Health, Harvard School of Public Health, Building I 1408, 665 Huntington Ave., Boston, MA 02115
• Email:
  dchristi@hsph.harvard.edu
• CAS Registry Number:
  Arsenic (CAS RN 7440-38-2)
• Federal Fiscal Year:
  2004
• Performing Organization:
  Harvard School of Public Health
• Peer Reviewed:
  True
• Start Date:
  20030701
• Source Full Name:
  Environmental Health Perspectives
• End Date:
  20050630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:3e11d4874231ee674790cf0d294cb73115c30b11e951fc3c194df5914dd4689caf53a3081ecc74a2c37c4d3116de9d8affbc530999ce4fe5acf1859caa1b6a0b
• Download URL:
  https://stacks.cdc.gov/view/cdc/214928/cdc_214928_DS1.pdf
• File Type:
  [PDF - 105.75 KB ]