Establishing an Imaging Protocol for Detection of Vascularity Within the Median Nerve Using Contrast-Enhanced Ultrasound

Details

• Personal Author:
  Buford JA ; Evans KD ; Hutmire CM ; Pargeon RL ; Roll SC ; Sommerich CM ; Volz KR
• Description:
  This preclinical study was conducted to develop discrete sonographic instrumentation settings and also safe contrast dosing that would consistently demonstrate perineural vascularity along the median nerve. This set of imaging studies was conducted with a convenience cohort of young adult female monkeys (Macaca fascicularis). Sonographic equipment settings and dosing were refined throughout the imaging series to ensure consistent contrast-enhanced ultrasound imaging. A mechanical index of 0.13 was consistently used for imaging. Perineural vessels were imaged with a suspension solution of 0.04 mL Definity/0.96 mL saline introduced over 5 minutes for a total dose of 0.8 mL of contrast solution. Blinded studies of high and low dose contrast, along with saline injections, were correctly identified by two experienced sonographers. This preclinical study established adequate equipment settings and dosing that allowed for a valid demonstration of vascularity surrounding the median nerve. [Description provided by NIOSH]
• Subjects:
  Animals Musculoskeletal System Nervous System Occupational Health Safety
• Keywords:
  Animal Studies Author Keywords: Contrast-enhanced Ultrasound Imaging Techniques Intraneural Vascularity Nerves Nerve Tissue Perineural Vascularity Ultrasound Upper Extremities
• ISSN:
  1552-5430
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Ohio ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  201-207
• Volume:
  29
• Issue:
  5
• NIOSHTIC Number:
  nn:20056563
• Citation:
  J Diagn Med Sonogr 2013 Sep; 29(5):201-207
• Contact Point Address:
  Kevin D. Evans, PhD, School of Health and Rehabilitation Sciences, The Ohio State University, 453 W. 10th Avenue, 340 A Atwell Hall, Columbus, OH 43210, USA
• Email:
  evans.36@osu.edu
• Federal Fiscal Year:
  2013
• Performing Organization:
  Ohio State University
• Peer Reviewed:
  True
• Start Date:
  20100901
• Source Full Name:
  Journal of Diagnostic Medical Sonography
• End Date:
  20130430
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:766ca230f98d2d6ed99cb644ef5442012f16eda70ce5310c8d1b9f99801ca079c1c59f70ca7cf741f4ac16eddca02fb0c0d5ed681fc2523f511ce69d28b7fca5
• Download URL:
  https://stacks.cdc.gov/view/cdc/214150/cdc_214150_DS1.pdf
• File Type:
  [PDF - 240.18 KB ]