Endocrine Physiology in Relation to Sleep and Sleep Disturbances

Details

• Personal Author:
  Tasali E ; Van Cauter E
• Description:
  Sleep exerts important modulatory effects on most components of the endocrine system. Pathways mediating the impact of sleep on peripheral endocrine function and metabolism include the activity of the hypothalamic releasing and inhibiting factors on pituitary hormone release and the autonomous nervous system control of endocrine organs. Modulatory effects of sleep on endocrine release are not limited to the hormones of the hypothalamic-pituitary axes; these effects are also observed for the hormones controlling carbohydrate metabolism, appetite regulation, and water and electrolyte balance. Sleep loss is associated with disturbances of hormone secretion and metabolism, which may have clinical relevance, particularly as voluntary partial sleep curtailment has become a highly prevalent behavior in modern society. Reduced sleep quality also adversely affects endocrine release and metabolism. Evidence suggests that part of the constellation of hormonal and metabolic alterations that characterize normal aging may reflect the deterioration of sleep quality. Major metabolic diseases such as obesity, type 2 diabetes, and polycystic ovary syndrome are all associated with sleep disturbances, which may promote the development or exacerbate the severity of the condition. Strategies to reverse decrements in sleep quality may have beneficial effects on endocrine and metabolic function. [Description provided by NIOSH]
• Subjects:
  Blood Energy Metabolism Hematologic Diseases Occupational Health Safety Sleep Sleep Initiation And Maintenance Disorders
• Keywords:
  Autonomic Nervous System Blood Sugar Disorders Endocrine System Disorders Hormone Activity Metabolic Effects Obesity Pituitary Gland Disorders Sleep Deprivation Sleep Disorders
• ISBN:
  9781416066453
• Publisher:
  Elsevier Saunders
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Book
• Place as Subject:
  Illinois ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  291-311
• NIOSHTIC Number:
  nn:20052809
• Citation:
  Principles and practice of sleep medicine, 5th edition. Kryger MH, Roth T, Dement WC eds. St. Louis, MO: Elsevier Saunders, 2010 Nov; :291-311
• Editor(s):
  Kryger MH; Roth T; Dement WC
• Federal Fiscal Year:
  2011
• NORA Priority Area:
  Healthcare and Social Assistance
• Performing Organization:
  University of Chicago
• Peer Reviewed:
  False
• Start Date:
  20090901
• Source Full Name:
  Principles and practice of sleep medicine, 5th edition
• End Date:
  20150831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:250ac237d3c456fc51b0c61da3c05cefaad6832d32931140829fa0b7a14f75e179b51288b43a6f7b2531795f065628359cb666a48fb482f8526382568504070f
• Download URL:
  https://stacks.cdc.gov/view/cdc/212279/cdc_212279_DS1.pdf
• File Type:
  [PDF - 3.46 MB ]