Laboratory and Field Evaluation of a Personal Sampler for Engineered Nanoparticle Exposures

Details

• Personal Author:
  Casuccio G ; Leith D ; Lentz H ; Lersch T ; Marchese A ; Miller-Lionberg DD ; Volckens J
• Description:
  Effective assessment of nanoparticle exposures requires accurate characterization of the aerosol. Of increasing concern is personal exposure to engineered nanoparticles that are specifically designed for use in the nanotechnology sector. This presentation will describe the design, operation, and performance of a personal sampler that utilizes thermophoretic force to collect nanoparticles onto a standard TEM (transmission electron microscope) grid. After collection, nanoparticles on the TEM grid are analyzed with an electron microscope, and the resultant data used to determine the characteristics of the nanoparticle aerosol sampled. Further analysis of the collected nanoparticles using energy dispersive spectroscopy allows discriminating engineered nanoparticles that may be of particular concern, from nanoparticles of natural or incidental sources. Thus, the TPS allows evaluation of the potential health risk due to exposure to specific, engineered nanoparticles independently of the potential risk posed by exposure to other aerosol particles that may be present at the same time. Laboratory experiments were conducted to determine the inlet losses and collection efficiency of the thermophoretic sampler for particles between 20 and 600 nm in diameter. These results are used together with theory for thermophoretic velocity to form a transfer function that relates the properties of the collected particles to the properties of the sampled aerosol. The transfer function utilizes a normalization factor, F(d), which is larger than unity for very small particles but approaches unity for particles larger than about 70 nm. We have also demonstrated TPS performance for sampling and discriminating engineered and non-engineered nanoparticles in the field. [Description provided by NIOSH]
• Subjects:
  Aerosols Environmental Exposure Occupational Health Risk Assessment Risk Factors Safety
• Keywords:
  Electron Microscopy Exposure Levels Hazards Measurement Equipment Nanoparticles Nanotechnology Risk Assessment Risk Factors Spectroscopes
• Publisher:
  Institut National de Recherche et de Sécurité (INRS)
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary
• Place as Subject:
  Colorado ; OSHA Region 8
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  41
• NIOSHTIC Number:
  nn:20052238
• Citation:
  Airmon 2014: The 8th International Symposium on Modern Principles of Air Monitoring and Biomonitoring, June 15-19, 2014, Marseille, France. Paris: Institut National de Recherche et de Sécurité (INRS), 2014 Jun; :41
• Contact Point Address:
  David Leith, Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, 80523
• Federal Fiscal Year:
  2014
• Performing Organization:
  Colorado State University - Fort Collins
• Peer Reviewed:
  False
• Start Date:
  20080701
• Source Full Name:
  Airmon 2014: The 8th International Symposium on Modern Principles of Air Monitoring and Biomonitoring, June 15-19, 2014, Marseille, France
• End Date:
  20110630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:707eb057160e699affce52d204585659f5c9fadac070d3ecc38a5b7f365a05b5f7ba704501563f6acc23a14411cd055a996aaa0fbd38204c1b523d634591b67b
• Download URL:
  https://stacks.cdc.gov/view/cdc/211796/cdc_211796_DS1.pdf
• File Type:
  [PDF - 211.00 KB ]