Details:

Alternative Title:
PLoS One
Publisher's site:
http://dx.doi.org/10.1371/journal.pone.0074276
Personal Author:
Reiter, Paul L. ; Katz, Mira L. ; Ruffin, Mack T. ; Hade, Erinn M. ; DeGraffenreid, Cecilia R. ; ... More +
Reiter, Paul L. ; Katz, Mira L. ; Ruffin, Mack T. ; Hade, Erinn M. ; DeGraffenreid, Cecilia R. ; Patel, Divya A. ; Paskett, Electra D. ; Unger, Elizabeth R. ; Less -
Description:
Background Cervical cancer incidence and mortality rates are high among women from Appalachia, yet data do not exist on human papillomavirus (HPV) prevalence among these women. We examined the prevalence of genital HPV among Appalachian women and identified correlates of HPV detection. Methods We report data from a case-control study conducted between January 2006 and December 2008 as part of the Community Awareness, Resources, and Education (CARE) Project. We examined HPV prevalence among 1116 women (278 women with abnormal Pap tests at study entry [cases], 838 women with normal Pap tests [controls]) from Appalachian Ohio. Analyses used multivariable logistic regression to identify correlates of HPV detection. Results The prevalence of HPV was 43.1% for any HPV type, 33.5% for high-risk HPV types, 23.4% for low-risk HPV types, and 12.5% for vaccine-preventable HPV types. Detection of any HPV type was more common among women who were ages 18–26 (OR = 2.09, 95% CI: 1.26–3.50), current smokers (OR = 1.86, 95% CI: 1.26–2.73), had at least five male sexual partners during their lifetime (OR = 2.28, 95% CI: 1.56–3.33), or had multiple male sexual partners during the last year (OR = 1.98, 95% CI: 1.25–3.14). Similar correlates were identified for detection of a high-risk HPV type. Conclusions HPV was prevalent among Appalachian women, with many women having a high-risk HPV type detected. Results may help explain the high cervical cancer rates observed among Appalachian women and can help inform future cervical cancer prevention efforts in this geographic region.
Subject:
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Adolescent
Adult
Female
Health Knowledge, Attitudes, Practice
Humans
Male
Nutrition Surveys
Papillomaviridae
Papillomavirus Infections
Prevalence
Risk Factors
Young Adult

Source:
PLoS One. 2013; 8(8).
Document Type:
Journal Article ;
Funding:
P30CA016058/CA/NCI NIH HHS/United States ; P50 CA105632/CA/NCI NIH HHS/United States ; P50CA105632/CA/NCI NIH HHS/United States ;
P30CA016058/CA/NCI NIH HHS/United States ; P50 CA105632/CA/NCI NIH HHS/United States ; P50CA105632/CA/NCI NIH HHS/United States ; Less -
Place as Subject:
Appalachian Region ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:30cbd4bc484b1834f1b067670ae91a061ce7432e3dde979346c87c19c8b6a1ee
File Type:

Supporting Files

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