Developing a Rapid Screening Method for Direct Visualization of Nanoparticles Captured on Filter Media During Occupational Exposure Assessments

Details

• Personal Author:
  Brenner SA ; Eastlake AC ; Neu-Baker NM
• Description:
  Best-known methods for ENM exposure assessment are based on using real-time direct-reading instruments (DRIs) to measure airborne particle counts and filter-based methods collected in tandem for off-line direct visualization by transmission electron microscopy (TEM) and for elemental analysis. Direct visualization by TEM is based on methods developed two decades ago for micron-sized asbestos and is low-throughput, expensive, and time- and resource-intensive. Therefore, the overarching goal of this project is to rapidly advance exposure assessment for the nanotechnology workforce by developing and testing a new protocol using enhanced darkfield microscopy (EDFM) with hyperspectral imaging (HSI) and mapping. EDFM-HSI combines imaging and spectrophotometry to identify, locate, and map ENMs within a sample based on the unique spectral response. Preliminary work has explored the use of EDFM-HSI for the analysis of silicon dioxide nanoparticles (NPs) captured on mixed cellulose ester (MCE) filter media. [Description provided by NIOSH]
• Subjects:
  Cellulose Esters Microbiology Occupational Health Safety Spectrum Analysis
• Keywords:
  Author Keywords: Mixed Cellulose Ester Cellulose Fibers Darkfield Microscopy Electrical Equipment Electron Microscopy Exposure Assessment Filters Hyperspectral Imaging Imaging Techniques MCE Microscopic Analysis Microscopy Nanoparticles Nanotechnology Optical Aids Optics Organic Compounds Reference Spectral Library Spectral Angle Mapper Spectrographic Analysis Spectrophotofluorometry Spectroscopes Visual Images

  More +
• ISBN:
  9780997511789
• Publisher:
  TechConnect
• Document Type:
  Text
• Genre:
  Proceedings
• Place as Subject:
  New York ; Ohio ; OSHA Region 2 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  EID - Education and Information Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  333-336
• Volume:
  1
• NIOSHTIC Number:
  nn:20050452
• Citation:
  Advanced Materials -TechConnect Briefs. Laudon M, Romanowicz B, eds. Austin, TX: TechConnect, 2017 May; 1:333-336
• Contact Point Address:
  Nicole M. Neu-Baker, State University of New York (SUNY), Polytechnic Institute, Colleges of Nanoscale Science and Engineering, Albany; NY, United States
• CAS Registry Number:
  Cellulose (CAS RN 9004-34-6)
• Editor(s):
  Laudon M; Romanowicz B
• Federal Fiscal Year:
  2017
• NORA Priority Area:
  Manufacturing
• Peer Reviewed:
  False
• Source Full Name:
  Advanced Materials -TechConnect Briefs 2017
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f97694dbff3f272893f31ac17376ac25ba1ff1984c843aabf175a62485df26338702689d7a5b4345e327aa34e2669695bae41cc160c4036304c6a76529ed3aa6
• Download URL:
  https://stacks.cdc.gov/view/cdc/210783/cdc_210783_DS1.pdf
• File Type:
  [PDF - 916.11 KB ]