Potential Applications and Human Biosafety of Nanomaterials Used in Nanomedicine

Details

• Personal Author:
  Bowman L ; Ding M ; Gu Y ; Su H ; Wang Y ; Zhao J
• Description:
  With the rapid development of nanotechnology, potential applications of nanomaterials in medicine have been widely researched in recent years. Nanomaterials themselves can be used as image agents or therapeutic drugs, and for drug and gene delivery, biological devices, nanoelectronic biosensors or molecular nanotechnology. As the composition, morphology, chemical properties, implant sites as well as potential applications become more and more complex, human biosafety of nanomaterials for clinical use has become a major concern. If nanoparticles accumulate in the human body or interact with the body molecules or chemical components, health risks may also occur. Accordingly, the unique chemical and physical properties, potential applications in medical fields, as well as human biosafety in clinical trials are reviewed in this study. Finally, this article tries to give some suggestions for future work in nanomedicine research. [Description provided by NIOSH]
• Subjects:
  Chemistry Delivery Of Health Care Drug Therapy Hazardous Substances Health Care Facilities Workforce And Services Occupational Health Safety Toxicology
• Keywords:
  Author Keywords: Nanoparticles Bioaccumulation Biological-effects Biological-systems Biomedical Engineering Biosafety Biosensors Chemical Properties Clinical Tests Clinical Trials Drug Therapy Health-care Health-engineering Health-hazards Human Biosafety Humans Imaging Techniques Medical-care Medical-equipment Medical Research Molecular Structure Nanomaterials Nanomedicine Products Nanoparticles Nanoscale Nanostructures Nanotechnology NPs Pharmacology Physical And Chemical Properties Physical Properties Potential Applications Therapeutic-agents Toxic-effects Toxic-materials

  More +
• ISSN:
  0260-437X
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  3-24
• Volume:
  38
• Issue:
  1
• NIOSHTIC Number:
  nn:20049964
• Citation:
  J Appl Toxicol 2018 Jan; 38(1):3-24
• Contact Point Address:
  Jinshun Zhao, Department of Preventative Medicine, Zhejiang Provincial Key Laboratory of Pathological and Physiological Technology, School of Medicine, Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang Province 315211, People's Republic of China
• Email:
  zhaojinshun@nbu.edu.cn
• Federal Fiscal Year:
  2018
• NORA Priority Area:
  Manufacturing
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Applied Toxicology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:77e5d1b239ca4c70152a5feb62b096e650c241287221a150abe899b765530f1ccc43b0c34c73b8c9c11c5e3cba741a7e51c4f279610ba49cdb016edf49c6189b
• Download URL:
  https://stacks.cdc.gov/view/cdc/210539/cdc_210539_DS1.pdf
• File Type:
  [PDF - 395.33 KB ]